Molecular Characterization of the Circulating Avian Infectious Bronchitis Viruses in the Mekong Delta Provinces in Vietnam
Molecular Characterization of the Circulating Avian Infectious Bronchitis Viruses in the Mekong Delta Provinces in Vietnam
Nguyen Phuc Khanh1*, Tran Ngoc Bich1, Nguyen Thi Cam Loan2, Chau Thi Huyen Trang1, Nguyen Thanh Lam1, Pham Quynh Yen Thanh1, Nguyen Thi Thuy Hang3
ABSTRACT
Avian infectious bronchitis (IB) is an acute respiratory disease affecting the poultry industry worldwide. The S1 sequences of infectious bronchitis virus (IBV) were used to characterize the genetic diversity of the virus in broiler chickens in Vietnam from 2022 to 2023. Phylogenetic and pairwise sequence analyses classified the detected IBV strains into two groups. Group 1 (IBV IBV-VN-CTU-ST1 and IBV-VN-CTU-VL1) was clustered to lineage GI-1 (Genotype Massachusetts) and shared 97.05 – 98.83% and 94.95 – 97.89% nucleotide and amino acid similarities, respectively. In addition, amino acid sequences of S1 region in both strains differ 33 positions with IBV vaccine strain H120 (KF188436). Meanwhile, IBV detected strains in Group 2 (IBV-VN-CTU-ST2, IBV-VN-CTU-VL2, and IBV-VN-CTU-VL3) were clustered to lineage GI-13 (genotype 4/91) and shared 97.80 – 98.56% nucleotide similarity and 96.42 – 97.89% amino acid similarity. Substitutions were identified at 34 of 547 amino acid positions compared to the 4/91 strain. Moreover, the amino acid sequences of the detected strains in the GI-1 and GI-13 lineages contained HVR1 and HVR-2 regions compared to the vaccine strain. This study illustrates the coexistence of the IBV lineages GI-1 and GI-13 in Vinh Long and Soc Trang provinces (The Mekong Delta provinces), Vietnam.
Keywords | Chicken, Infectious bronchitis virus, S1, Vietnam
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June 2025
Adv. Anim. Vet. Sci., Vol. 13, Iss. 6,
