Association Analysis of Polymorphisms in PLIN1 Gene with the Body Weight of Ross-308 Broiler Chickens
Association Analysis of Polymorphisms in PLIN1 Gene with the Body Weight of Ross-308 Broiler Chickens
Ali A. Abdulkareem1*, Salah H. Faraj2, Mohammed Sabeeh Majeed3, Widya P. B. Putra4, Ratna S. Harahap5
ABSTRACT
Perilipin 1 (PLIN1) gene is one of the candidate gene to improve the body weight of chicken. This study aimed to determine the association between chicken PLIN1 gene polymorphisms with body weight of Ross-308 Broiler chicken. The blood samples from one-hundred unsexed birds were used in the present study for the DNA sequencing analysis. The sequencing analysis revealed two transition mutation sites of g.1912C>T and g.2308C>T in the PLIN1 gene of birds under study. The polymorphic informative content (PIC) in both mutation sites were classified in low category (PIC<0.30). The C allele was the common allele (±80%) in both mutation sites. The polymorphisms of PLIN1 gene were not significantly associated with body weight. In conclusion, the polymorphisms of Perilipin 1 gene cannot be used as a genetic indicator for body weight of chickens.
Keywords | Body weight, Genetic polymorphisms, PLIN1 gene, Chicken
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July 2025
Adv. Anim. Vet. Sci., Vol. 13, Iss. 7,
