A, Mean (±SEM) changes in plasma leptin levels (ng/ml) before and after saline/NMS administration (at 0 min) in normal fed adult male monkeys. *P<0.05, ***P<0.001 vs 0 min sample (ANOVA followed by post hoc Dunnett’s test). B, Comparison of mean (±SEM) plasma leptin levels (ng/ml) in 60 min pre- and 120 min post saline/NMS in normal fed adult male monkeys. **P<0.01 vs pre-treatment (Student’s t test).