Effect of thiram and Salvia miltiorrhiza (SM) therapy on serum AST, ALT, ALP activity (A-C) and antioxidant biomarkers (SOD, GSH-Px) and MDA content (D-F). Thiram caused decrease in serum ALP activity and increase in ALT and AST contents. SM therapy caused an increase in ALP levels with a decrease in serum ALT and AST levels (A-C). The antioxidants SOD and GSH-Px were decreased while the MDA content was increased in thiram-fed group. SM therapy restored and increased antioxidant markers (SOD and GSH-Px) with a decrease in MDA contents (D-F). The data are expressed as the mean ± SD *P<0.05 among groups (n=10/group).