MSCCM reduces the collagen generation in MRC-5 cells. A, the collagen content was examined using Sircol soluble collagen assay in control cells (Con), single-irradiated MRC-5 cells (IR), and irradiation + MSCCM treated MRC-5 cells (IR+MSCCM). B-C, mRNA levels of Col1A1 (B) and Col1A2 (C) were detected by q-PCR. D-E, protein levels of Col1A1 (D) and Col1A2 (E) were detected by western blot. Data are expressed as the mean ± SD (n=5). *p< 0.05, ** p<0.01, ***p<0.001.