Modulatory effect of BHS-1 on expression of Cox-2, MMP-2 and -9 in response to chronic exposure of BaP: A, A549 and A549/B cells were treated with DMSO and BHS-1 (15μM) for 24 h and expressions of Cox-2, MMP-2 and -9 were determined by Western blot analysis; B, protein expressions from 3 different experiments were quantified by densitometry analysis. Similar superscript letters having * differ significantly with similar superscript letters without * at P<0.05.