hGFAP-DsRed transgenic Guangxi Bama mini-pig founders showed normal health and development. The hGFAP-DsRed transgenic founders were clinically healthy and developed normally after birth (A), two months old (B) and more than one year old (C). Histological analysis showed that the various brain regions including cerebral cortex (D), olfactory bulb (E), hippocampus (F), substantia nigra (G), cerebellum (H), spinal cord (I) as well as liver (J) and pancreas (K) of the hGFAP-DsRed transgenic founders were normal. (Scale bars = 25 μm).