The immunohistochemical staining of MRP1 in rat liver sections was implemented by FITC-conjugated IgG and MRP1 antibody (green) and the nuclei were counterstaining with DAPI (blue). Control group (a) and CSO-treated group (b) showed low MRP1 concentration. The group that was treated with liposomal-doxorubicin (c) demonstrated highly induced MRP1 concentration compared to control group. CSO/liposomal-doxorubicin group (d) showed a highly decreased MRP1, compared to DOX-treated group. The sections were analyzed under fluorescence microscope (Magnification x200).