Measurement of DNA damage in Snuff and Charas-addicted active smokers. A, comparison of DNA damage by showing comets among different groups of active smokers. In addition to smoking, DNA damage was significantly increased with consumption of charas and snuff. Compared to active smokers, the length of the comet was found longer in charas and snuff-addicted active smokers. B, quantitative analysis among charas and snuff-addicted smokers. A, B and C are the Duncan’s variables representing statistical significance among groups. Quantitative analysis showed that charas-addicted active smokers have highest TCS value among all three groups. However, the TCS values of snuff-addicted people were also higher than those who did smoking only (*p˂0.05).