Production of signaling molecules (e.g., AHLs) in sterile supernatants of C. fruendii B1. A shows the production of signaling molecules by A136 biosensor and B indicates determination of signaling molecules by CV026 biosensor. Mainly, B1 represents sterile supernatants of the bacterial strain C. freundii B1, showing AHL production, 3OC6-HSL is a synthetic AHL represents positive control and LV4 (sterile supernatants of Staphylococcus epidermis) shows negative control in well diffusion bioassay.