Fig. 2.

FAR amino acid sequence alignment. Alignment of EpFAR and other known amino acid sequences corresponding to the sequences specified in the Table I. The ER membrane retention signals are marked with a box. On top of the alignment, the regions corresponding to the predicted transmembrane domains (TMH) of EpFAR are marked as follows: TMpred TMH are marked with a solid line (top: 23-39aa, 256-276aa, 354-372aa, 377-395aa, 500-520aa), predictions by TOPCONS are marked with a dotted lines (second from the top: 22-42aa, 379-399aa, and 498-518aa), while the TMHMM predictions are marked with dashed line (bottom: 494-516aa).