Changes in CYP1A1 mRNA and protein expression in different drug groups treated with AZA. Cells were cultured for 12 h with each of the anti-tuberculosis drugs (isoniazid, INH; pyrazinamide, PZA; INH + rifampicin, RIF; or INH + RIF + PZA) or their combination with AZA (10 μM). (A) CYP1A1 mRNA expression was detected by quantitative real-time PCR. (B) CYP1A1 protein expression was detected by ELISA. Each group included 6 parallel samples, each of which was measured 3 times.