Effect of prior administration of curcumin (100 mg/kg/day) for 15 days on cataleptic behavior induced by rotenone observed in inclined plane apparatus. Values are mean+SD (n=6). Data was analyzed by one-way ANOVA followed by Tukey’s post-hoc test. Mean values were significantly different from controls (**p<0.01), and rotenone (n=6) injected rats (++p<0.01). The group that underwent successive rotenone administration for eight days exhibited a prominent cataleptic behavior as evident by significant increase in % cataleptic score as compared to control rats. Pre-treatment with curcumin significantly normalized these observed parameters in Cur+Rot group. Cataleptic score in % was calculated by (latency to move/total time) x 100).