Fig. 4.

Effect of pathological changes in hippocampus of mice with repeated cerebral ischemia-reperfusion model; A: Blank Group; B: Model Group; C: Nimodipine Group; D: Naoluotong Group; E: High-dose Spatholobus Grandiflprum Group; F: Mid-dose Spatholobus Grandiflprum Group; G: Low-dose Spatholobus Grandiflprum Group; -: Brain cells in the hippocampus are normal; +: brain hippocampus, individual nerve cells edema, scattered, individual neuron degeneration, cytoplasm lightly stained, fuzzy structure; ++: a few hippocampal edema in the hippocampus of the brain, a few neuron degeneration, cytoplasm Light staining, fuzzy structure; ++: cerebral hippocampal neuronal edema, most of the neuron necrosis.