Gene ontology enrichment analysis of DEmRNAs. (A) GO biological process classification of up-regulated mRNAs. A1: mRNA metabolic process, A2: gene expression, A3: immune system process, A4: cellular macromolecule metabolic process, A5: establishment of protein localization to membrane, A6: protein targeting to ER, A7: response to stress, A8: SRP-dependent cotranslational protein targeting to membrane, A9: establishment of protein localization to endoplasmic reticulum, A10: cellular component organization or biogenesis; (B) GO cellular component classification of up-regulated mRNAs. B1: intracellular part, B2: intracellular, B3: membrane-bounded organelle, B4: intracellular membrane-bounded organelle, B5: intracellular organelle part, B6: intracellular organelle, B7: organelle part, B8: nucleus, B9: macromolecular complex, B10: nuclear part; (C) GO molecular function classification of up-regulated mRNAs; C1: poly(A)RNA binding, C2: RNA binding, C3: protein binding, C4: binding ,C5: nucleic acid binding, C6: organic cyclic compound binding, C7: heterocyclic compound binding, C8: structural constituent of ribosome, C9: enzyme binding, C10: protein complex binding; (D) GO biological process classification of down-regulated mRNAs; D1: regulation of multicellular organismal process, D2: regulation of cell morphogenesis involved, D3: regulation of multicellular organismal development, D4: system development, D5: nervous system development, D6: regulation of development process, D7: multicellular organismal development, D8: forebrain development, D9: positive regulation of potassium ion, D10: regulation of cell differentiation; (E) GO cellular component classification of down-regulated mRNAs; E1: intrinsic component of plasma membrane, E2: integral component of plasma membrane, E3: plasma membrane part, E4: apical part of cell, E5: apical plasma membrane, E6: cell periphery, E7: plasma membrane, E8: sodium potassium-exchanging ATPase complex, E9: cation-transporting ATPase complex, E10: plasma membrane region; (F) GO molecular function classification of down-regulated mRNAs; F1: cation transmembrane transporter activity, F2: ion transmembrane transporter activity, F3: anion cation symporter activity, F4: transmembrane transporter activity, F5: substrate-specific transporter activity, F6: substrate-specific transmembrane transporter activity, F7: RNA polymerase II transcription regulatory, F8: monovalent inorganic cation transmembrane transporter, F9: sequence-specific DNA binding RNA polymerase, F10: metal ion transmembrane transporter activity.