John Gachohi, Simon Karanja, Salome Wanyoike, Nduhiu Gitahi, Salome Bukachi, Kenneth Ngure
...ospirosis is a neglected zoonosis and an emerging urban slum health problem. There is a scarcity of population-based information on the distribution of the infection and transmission determinants for urban Leptospirosis in developing countries. This study aims to source dynamic ecological and epidemiological field parameters to describe a slum household-based pathogenic Leptospira population dynamics simulation model. The model will be analyzed to assess the r...
Wesam Hasan Mohamed Mady 1*, Bing Liu2, Dong Huang2, A. Arafa1, M.K. Hassan1, M.M. Aly1, Pucheng Chen2, Yongping Jiang2* and Hualan Chen2
...d poultry and to contain zoonosis. The primary goal of this study was to develop H9 plasmid-based DNA vaccine against the currently circulating AIV subtype H9N2 targeting HA gene of the virus A/Turkey/Egypt/1341V/2013(H9N2). The full length sequence of HA gene was codon optimized to the chicken biased codons and subcloned into the pCAGGS plasmid vector under the control of the chicken β-actin promoter. The in vitro expression of recombinant plasmid DNA wa...
Naimat Ullah Khan1,2, Muhammad Hassan Saleem1, Aneela Zameer Durrani1, Nisar Ahmad3, Ayesha Hassan1, Sultan Ayaz2, Sajid Umar4, Muhammad Luqman Sohail5,*, Muhammad Shafee6, Ikramullah Khan7, Mumtaz Ali Khan1, Azmat Ullah Khan8, Naimat Ullah Malik1 and Abdul Razzaq9
Tahir Iqbal1, Umer Rashid1*, Naveed Shahzad2, Amber Afroz1, Muhammad Faheem Malik3 and Muhammad Idrees4
...ealth risk in context of zoonosis and food borne transmission if aHEV emerges as zoonotic HEV.
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Zhijun Zhong1, Rui Tu1, Xichun Wang2, Yi Geng1, Qicheng Xiao1, Yinan Tian1, Bin Wei1, Jiaming Dan1, Ya Wang1 and Guangneng Peng1,*
...ucellosis is a worldwide zoonosis that is primarily caused by Brucella melitensis, Brucella abortus, Brucella suis, and Brucella canis. However, in China, information regarding brucellosis in pet dogs caused by B. canis is limited. In the present study, we conducted a comprehensive molecular, pathological, and immunohistochemical analysis to detect this pathogen in pet dogs. Molecular methods, combining three types of PCR assays, identifie...
Parakriti Gupta1, Kapil Goyal2 and Mini Pritam Singh3*
Hepatitis E Virus and Zoonosis
...where the infection is a zoonosis. Though the virus has only one serotype, 8 genotypes have been documented. Out of these, HEV 1 and 2 have been reported from developing countries and are transmitted mainly through faeco-oral route while HEV 3 and 4 are reported from developed countries and the infection is acquired by humans due to the eating of undercooked pigs, deer and wild boar meat. Recently HEV genotypes 5 and 6 have been reported in Japanese wild boars...
Xinjun Zhang1,2, Pengyong Wang1,2, Huimin Ju1,2, Yanhong Wang1,2, Yang Yang1,2* and Guoqiang Zhu1,2*
... a certain potential for zoonosis....
Salvator Minani1,2*, Eric Nsengiyumva1, Anatole Bigirimana1,2, Arnaud Cubahiro1,2, Dieudonné Ntakirutimana1,2 and Vénuste Bizoza1,2
...cioliasis is a parasitic zoonosis caused by Fasciola hepatica and Fasciola gigantica affecting mainly domestic ruminants and occasionally humans. Due to the lack of epidemiological studies of fascioliasis in Burundi, this study was carried out to assess the prevalence of fascioliasis by liver inspection in slaughtered ruminants at Muyinga slaughterhouse. The liver of each slaughtered domestic ruminant was inspected, palpated and incised to look for flukes in t...
Amthal Ahmed Fouad1, Basem Mohamed Ahmed2, Momtaz Abdelhady Shahein1, Hussein Aly Hussein2*
...rabies is a major global zoonosis and is endemic in Egypt. Rabid dogs are the prime source for human and livestock Lyssavirus rabies (RABV) exposure with almost 100% case fatality. While all lyssavirus rabies genetic data -including whole genomes- from Egypt are clustered within a unique lineage (Africa-4 lineage of the cosmopolitan clade), no report provided detailed description of this lineage genome and the last published whole genome dates back to 2009. In...
Saloua Ziani1*, Khalid Sohaib2 , Youssef Lhor3, Ikhlass El Berbri4, And Ouafaa Fassi Fihri4
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Tariq Jamil1, Muhammad Saqib2*, Abid Rashid3, Muhammad Hammad Hussain4, Khushal Khan Kasi5, Muhammad Haleem Tayyab2, Muhammad Azam Kakar5, Heinrich Neubauer1 and Mudassar Iqbal6*
...ucellosis is a worldwide zoonosis. It is transmitted by direct contact or consumption of contaminated unpasteurized dairy milk. A total of 193 sera were collected from occupationally exposed participants in Quetta, Pakistan and analyzed by Rose Bengal Plate Test (RBPT). An overall 4/193 (2.1%, CI 0.6-5.2) seropositive were found. A higher seropositive rate was found in participants with >40 years age, livestock contact, poor socioeconomic group and no raw m...
Abdul Kabir1*, Anees Ur Rahman2, Inzamam Ali Shah2, Ibad ur Rahman2
...ox is a contagious viral zoonosis that affects buffaloes, cows, and humans. It is caused by buffalopox virus (BPXV), a member of the genus Orthopoxvirus and a close variant of vaccinia virus (VACV). Buffalopox was first reported in India in 1934 and has since become an emerging and re-emerging disease in the Indian subcontinent and other countries. The disease is characterized by pock lesions on the skin and mucous membranes of the affected animals and humans,...
Muhammad Wasif Gulzar*, Riffat Maqsood, Muhammad Zain, Muhammad Suleman, Tayyab Ur Rehman, Sana Asif, Abdul Wadood and Jawad Hussain
...o;s defenses. As a major zoonosis, initial treatment and successful preventive and control efforts depend on a clear and prompt diagnosis. For the diagnosis of Rabies, conventional techniques such as Direct Fluorescent Antibody Test (dFAT) and histopathology are still employed. The OIE and WHO both frequently propose the gold standard test, the Direct Fluorescent Antibody Test (dFAT), for the diagnosis of Rabies in fresh canine brain tissues. The preferred met...
