De-Yong Zhang1, Xiao-Lu Xu1,*, Qin Ruan2, Xiu-Ying Shen3 and Yin Lu1
...mine the subchronic male reproductive toxicity of PFOS, male mice were administrated with a serial dosage of PFOS for 90 days for testicular observation and spermatogenesis evaluation. PFOS ≥ 11 mg/kg (accumulative dosage) resulted in visible histopathological changing in testis, including disorder and vacuolization of spermatogenic cells. Changed testicular organ coefficient (for dosage ≥ 55 mg/kg), decreased sperm concentration (for 110 mg/kg dosage), ...

Pakistan Journal of Zoology


Vol. 52, Iss. 4, Pages 1225-1630


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