Rida Zainab1, Sana Elahi1, Afshan Kaleem2,*, Daniel C. Hoessli3, Mehwish Iqtedar2, Roheena Abdullah2, Faiza Saleem2, Shanza Khan1, Anusha Ijaz1, Shagufta Naz2 and Abdul R. Shakoori4,5,*
...ke Parkinsonism and Hyperprolactinemia. A novel, computer-based drug designing technique, has emerged to develop more efficient drugs. One of the computational methods becoming increasingly popular to develop new drugs is relying on Pharmacophores. This method was utilized to develop pharmacophore models of Akt2 inhibitors and β2-Adrenoceptor agonists. A pharmacophore model is proposed, using fourteen second generation and one first generation antipsychot...
Memis Ozdemir
...in dairy cattle, because prolactin has an important regulatory role in the development of the mammary glands, the secretion of milk and the expression of milk protein genes. It has been seen many studies about Prl/RsaI polymorphism found in the exon 3 or exon 4 region of bovine prolactin gene in the literature. The aim of this study was to determine whether the DNA sequence of the Prl gene exon 3 or exon 4 in c...
Yan-Guo Han, Yu-Qing Han, Jia-Yuan Wu, Jia Guo, Ri-Su Na, Yan Zeng, Guang-Xin E, Yong-Ju Zhao and Yong-Fu Huang*
... respectively. Serum SS, prolactin (PRL), growth hormone (GH) and insulin-like growth factor 1 (IGF-1) concentrations were detected by radioimmunoassay. The offspring lambs in T group showed significantly lower serum SS and higher PRL concentrations than those in the control group, and there were no difference between T group and the control group in terms of serum GH and IGF-1 concentrations. There was a significant negative correlation between offspring lamb...
Jiao Qin,Qian-Qian Su and Quan-Sheng Liu*
... Cabergoline can inhibit prolactin (PRL) secretion and was applied in fertility control for animal, however, the physiological and behavioral mechanisms of cabergoline as a sterilant in practice remain little known. This study determined the effects of different doses of cabergoline on the inter- and intra-sexual social behavior and reproduction physiology in adult female lesser rice-field rats, Rattus losea. Results showed that the ovary weight of fema...
Khayyam1*, Muhammad Zahid1, Naiz Ali2 and Qadeem Khan3
...3±4.83years). The prolactin in HT females and males showed significantly high values (p=0.041, 0.025respectively) but follicle stimulating hormone was significantly low (p=0.0007) in female HT patients. Follicle stimulating hormone and Luteinizing hormone concentrations were higher than normal range in both male and female Grave’s disease patients. Prolactin and serum gonadotropin showed fluctuatio...
Hamdy Abdala Elnagar, Wael Mohamed Wafa*, Abdelaziz Mustafa Sakr, Mohammed Mahmoud Hegazy
...erone (TES), leptin, and prolactin (PRL) in the blood and their relationships with age advancing of Egyptian buffalo males from one up to 24 month of age. Blood samples were taken from 66 male buffalo calves at 1, 3, 6, 12, 18 and 24 month of age (11 animals at every age). TES, leptin and PRL levels were determined in blood plasma. Results showed insignificant increase in TES and PRL by age advancing at 1-3 month, and in leptin at 1-6 month of age. All hormone...
Hayrettin Çayiroglu1*, Füsun Coskun1, Hüseyin Çayan1, Ayse Gül Filik2 and Ahmet Sahin1
...m triglyceride level and prolactin hormone level increased by fenugreek seed supplementation (P<0.05). Fenugreek seed supplementation did not affect milk organoleptic properties such as smell, taste and appearance. To conclude, fenugreek seed in lactating goats can be used as natural supplement to increase milk yield since fenugreek seed had no effect on sensory properties of milk....
Ngoc Tan Nguyen1*, Tan Loi Le1, Thi Kim Ngan Vo1, Chi Hieu Do1, Tuan Thanh Hoang2, Nguyen Khang Duong3, Quang Minh Luu4
...ext-align: justify;">The prolactin (PRL) gene has previously been reported as a potential candidate for egg production in birds. This study identified the prolactin gene polymorphism in the exon 5 region and its association with reproductive traits of TB crossbred ducks. Three hundred and thirty-one crossbred ducks were used in this study, with blood samples collected from the wing vein for DNA extraction to amplify the frag...
Ngoc Tan Nguyen1*, Thi Tuong Vi Trang1, Thi Thuy Tien Nguyen2, Tuan Thanh Hoang2, Duc Thoa Nguyen2
...ymorphism of the chicken prolactin gene at the 24 bp indel locus in the promoter region was studied, together with its association with the reproductive traits of color dual-purpose VLV hens. Egg production parameters were recorded as age at first egg (AFE; days), body weight at first egg (BWFE; gram/bird), mean egg weight (MEW; gram), and accumulated number of eggs (ANE) up to 38 weeks of age. DNA collected from the wing vein at 38 weeks of age was extracted ...
