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 Mukhtiar Ahmed, Jana Pickova, Taufiq Ahmad, Muhammad Liaquat, Abid Farid, Muhammad Jahangir

...s generation of reactive oxygen precursors and free radicals. Oxidation affects many interactions among food constituents, leading to both desirable and undesirable products. Food lipids are the foods components that are most susceptible to oxidation, therefore oxidation reactions are one of the major sources of deterioration that occurs during manufacturing, storage, distribution and final preparation of foods. Lipid oxidation products are omnipresent in food...
Pinar Oztopcu-Vatan1, Gokhan Kus2, Emine Inan3, Melek Gunindi Korkut3, Selda Kabadere4,* and Ruhi Uyar4
...n inhibitor of both cyclooxygenase and lipoxygenase pathways of arachidonic acid metabolism, changes the survival rate and induces apoptosis in a hepatoma cell line (H4IIE). We determined in vitro survival rate with MTT assay, the morphological changes with an inverted microscope, apoptosis using flow cytometry and statistical significance with one way analysis of variance followed by Tukey’s multiple comparison...
Abdur Rahim1, Ghulam Abbas1,*, Sara Ferrando2, Lorenzo Gallus2 and Abdul Ghaffar3
... -20‰), dissolved oxygen (5.6 to 7.5ml/l), temperature (25°C to 28°C). pH (7.6-7.8), ammonia (NH4-N) and `nitrites (NO2-N) less than (0.001mg/l), Secchi’s disc visibility (8 cm to 46 cm). Higher percent weight gain (2665 g), specific growth rate (2.76±0.5 % day-1), best feed conversion ratio (0.14), condition factor (4.1), viscerosomatic index (7.1), hepatosomatic index (1.4) were signific...
Yang Wang1, Zhide Cheng2, Mengjie Tang3, Haixia Zhou1, Xiaolu Yuan4,Muhammad Aqeel Ashraf5, Shuting Mao1 and Jing Wang1,*
...educes the dependence on oxygen and enhances the adaptation to the hypoxic environments.
...
Abdul Malik1,4, Ghulam Abbas1*, Hameeda Kalhoro2, Illahi Bux Kalhoro3, Syed Sajjad A. Shah4 and Halima Kalhoro3 
...mn;0.2°C), dissolved oxygen (6.10±0.1 ml/l), pH (6.6±0.1 ml/l) and ammonia (0.02±0.004 ml/l) throughout the study period. Taking into consideration the number of fertilized eggs and survival of fry data attained in the present study, a salinity level of 20% is suggested for red tilapia breeding in concrete tanks.
...
Hameeda Kalhoro1, Abdul Malik2,Ghulam Abbas2,*, Illahi Bux Kalhoro3, Sajjad Ali Shah4and Haleema Kalhoro3
... 0.20 °C), dissolved oxygen (5.2 ± 0.11mg/L), pH (6.9 ± 0.15), ammonia (0.48 ± 0.02 1mg/L) and hardness (118 ± 2.4 mg/L). Our results indicated that better growth increment can be achieved on squid or pellet feed and so it is suggested that in similar culture conditions of Snakehead will be more profitable on pellet feed followed by squid feed.
...
Abdul Malik1,2, Ghulam Abbas1,*, Abdul Ghaffar3, Sara Ferrando4, Lorenzo Gallus4 and Syed Sajjad A. Shah2,3
...n;0.12°C), dissolved oxygen (6.4±0.02 mg/L), pH (7.47±0.04) and ammonia (less than 0.022±0.001 mg/L) were monitored throughout the study period. Water quality parameters remained within the recommended range. Our results suggest that Nile tilapia, O. niloticus may give maximum eggs up to 15‰ salinity with 92% survival of fry.
...
Abdul Malik1,2, Ghulam Abbas1,*, Abdul Ghaffar3, Ghulam Dastagir4, Sara Ferrando5, Lorenzo Gallus5, Asad Ali Muhammad1,6, Abdul Jabbar2 and Khalil-ur-Rehman2 
...mn;0.08°C, dissolved oxygen 7.48±0.06 mg/L, pH 7.64±0.04 and ammonia 0.022±0.004 mg/L. Relationship between log body weight and log total length of the the fish shows that Nile tilapia fingerlings reared from 10‰ - 20‰ was significantly (P <0.05) higher than 25% and 30% salinity levels. Present study suggests that Nile tilapia can be reared up to 20% salinity to get good growth and higher survival rate.
...
Nazish Shaukat1, Muhammad Javed1,Faiza Ambreen2* and Fariha Latif1
...he formation of reactive oxygen species (ROS) which ultimately leads to tissue damage and oxidation of biomolecules. Aquatic organisms possess antioxidant system to cope with the oxidative stress. This research was conducted to see the effect of lead on peroxidase activity (antioxidant enzyme) in the gills and liver of Labeo rohita. Experiment was conducted in the laboratory by exposing four groups of Labeo rohita to different doses of PbCl2...
Muhammad Kashif Maan1, Muhammad Arif Khan1, Shehla Gul Bokhari1, Muhammad Ijaz2, Hamid Akbar1, Sajid Umar 3 and Muhammad Luqman Sohail4,*
...ith isoflurane (4%) with oxygen flow rate of 1L/min. Rabbits administered with xylazine-ketamine anesthesia showed significant increase (P<0.05) in serum alanine aminotrasferase, aspartate transaminase and blood urea nitrogen as compared to isoflurane anesthesia; whereas, no statistical difference (P>0.05) was observed for alkaline phosphatase, creatinine and bilirubin between the two groups. Heart rate, blood pressure and saturation of

Muhammad Suhaib1*, Ijaz Ahmad2, Masooma Munir3, Badar-Uz-Zaman1, Bushra Atta4 and Muhammad Khubaib Abuzar5 

... stress certain reactive oxygen species are produced that damage the vital plant organelles causing disturbances in the normal functioning of the plant and even may lead to death in severe cases. The results of this study conferred that there were genotypic variation found in two genotypes regarding salinity tolerance. SARC-4 was found to tolerate more salt stress as compared to Parwaz-94 and performed better at both salinity levels then Parwaz-94. Salicylic a...
Ayesha Noreen1, Dilara A. Bukhari2 and Abdul Rehman1,*
....
...
Laiba Shafique1,*, Muhammad Afzal1, Syed Zakir Hussain Shah2, Mehroze Fatima3, Huma Naz4, Qaisra Saddique1
...aracteristics (dissolved oxygen, pH and temperature) were checked daily throughout the trail. Results concluded that the body mineralization in L. rohita was increased by supplementation of organic acid. The maximum body mineralization was noted in fish fed with the dietary group OA3 that contain citric acid and minimum mineralization was noted in the diet OA5 containing lactic acid when compared with other dietary treatments. In c...
Md. Abu Affan1,*, Abdulmohsin Al-Sofyani1, Adnan Jaman Turki2 and Mohammed S.B. Hariri3
...ischarges, low dissolved oxygen (DO), temperature, salinity, pH, ammonia, turbidity, pesticides, toxins, and diseases. The study was carried out to find out the reasons of sudden fish killing. Therefore, physico-chemical and biological parameters, and postmortem, especially the gills and gut content of dead fishes were studied. The dead Tilapia tilapia (Tilapia), Chanos chano (Milkfish) and Parapriacanthus ransonneti (Glassfish) were found...
Haozhen Liu1, Xiangfu Li2, Yinong Wang1,*, Xun Liu3,4, Li Wang1, Dong Liu1, Chen Chen1, Jinjing Li1, Haifeng Jiao5 and Zhongjie You1,5
...al phosphorus, dissolved oxygen and water colour are the certain environmental factors that have proved shaping the distribution of macrobenthic abundance, diversity and multivariate structure of the assemblages.
...
Song Jiang1,2, Fa-lin Zhou1, Qi-bin Yang1, Jian-hua Huang1, Li-shi Yang1 and Shi-gui Jiang1*
...mpacts of temperature on oxygen and energy metabolism in the hepatopancreas of the black tiger shrimp (Penaeus monodon) were investigated via the effects of thermal stress on superoxide anion (O2-) production, superoxide dismutase (SOD) activity, glutathione (GSH) and adenosine triphosphate (ATP) concentration, as well as nitric oxide synthase (NOS) activity and nitric oxide (NO) concentration catalyzed by NOS. Based on biochemical...
Asima Bano1, Hafiz Muhammad Tahir2, Hira Sherawat3, Muhammad Mutlib4, Muhammad Arshad5, Muhammad Akram Qazi6, Sajida Naseem5, Rabia Ishaq1, Iram Liaqat2 
...stress enzymes i.e., monooxygenases and glucathione S-transferases with breast cancer. For enzyme estimation plasma samples from the patients suffering from breast cancer and age matched healthy individuals (control) were collected. The results revealed decline in the level of these enzymes in breast cancer patients as compared to healthy individuals because of this decline the overall level of protein was also found to be decline. It is concluded from the stu...
Muhammad Usman Ahmadand Ikram-ul-Haq*
...% reduction in dissolved oxygen at pH 7.5, temperature 37°C, 25mM lactate as H+ donor after 20 min. This strain was later on confirmed by 16S ribotyping procedure. Oxyrase was used for improved cultivation of anaerobic bacteria by employing Hungate Technique where its antioxidant potential was compared with common reducing agent Cysteine-HCl (Cys-HCl). Four anaerobic bacterial strains (Anaerobaculum hydrogeniformans OS1, Akkermansia mu...
Kamran Zakaria1*, Noreen Munawar1 and Shafqat Ejaz2
...ys same role to earth as oxygen to body. In order to safe this Globe from droughts and floods, it is essential to design a strategy for the balanced usage of water resources for urban uses and agriculture. For such purpose, Precipitation regions were recognized in river Indus basin in Pakistan by examining the rainfall frequencies with the help of global wavelet power spectra. Records from 52 rain gauges were studied and the outcomes of the whole power spectra...

 Xu Lijie, Obaid Ullah, Liu Haixing, Ihsan Ali, Zhongshu Li* and Nan-Zhu Fang*

...accumulation of reactive oxygen species (ROS) is one of the reasons for the slow growth of mammalian preimplantation embryos. Peroxisome proliferators-activated receptor gamma (PPARγ) functions in the nuclear regulatory factor 2 (Nrf2) antioxidant pathways by binding to the promoters of antioxidant genes and regulates the expression of genes that associate with NADPH oxidase. To understand the role of PPARγ in the development of early embryos and d...
Rıfat Ertekin1*, Mete Ozkurt1, Gokhan Kus2 and Selda Kabadere1
...00 μM TA groups, cyclooxygenase-2 (COX-2) decreased incrementally compared to the control group. Considering overstimulation of COX-2 paths in emergence of cancer or in metastasis, this study shows TA has an antiproliferative and stimulating effects on apoptosis of LNCaP cells based on the dose and duration of exposure.
...
Sun Hong1, Zhang Yifeng1, Wang Baishi2, Li Yangwei1, Xu Wenbo1, Mao Runkun1 and Wang Zhenglong1,*
...burrow system to measure oxygen (O2) and carbon dioxide (CO2) concentrations and the temperature and humidity in the underground burrows of mandarin voles in Xinzheng, Henan Province, China during the spring and summer of 2015. Our results show that 1) the depth and complexity of the burrow were higher during summer than during spring; 2) maximal CO2 levels (2.55%) and minimal O2 levels (16.04%) were recorded in the ...
Muhammad Afzal1, Nighat Sultana1, Ali Hassan1, Syed Zakir Hussain Shah2,*, Mahroze Fatima3, Syed Makhdoom Hussain4, Muhammad Bilal5 and Majid Hussain2
...rature, pH and dissolved oxygen were monitored and maintained within acceptable limits for fish during entire experiment. The findings of the experiment showed improved weight gain%, specific growth rate (SGR), feed conversion ratio (FCR), muscle composition and digestibilities of dry matter, crude protein and crude fat in Labeo rohita juveniles when fed CA supplemented diet. Similar observations were also recorded for the group fed on PHY supplemented...
Maliha Ayub1, Muhammad Javed1, Fariha Latif 1*, Faiza Ambreen2, Komal Sabir1
...les against the reactive oxygen species (ROS) and their harmful effects. This study was aimed to evaluate the effects of sub-lethal concentrations of manganese on antioxidant activity in the fish, Labeo rohita. Fish were acclimatized for two weeks in the cemented tanks prior to the start of experiment. Four groups (n=10) of one year old fingerlings of Labeo rohita were exposed to 96-hr LC50 and sub-lethal concentrations (2/3rd
S. Jalbani1, N.T. Narejo2,* and P. Khan2 
 

 

..., temperature, dissolved oxygen; ammonia nitrate and alkalinity were monitored fortnightly and found within the suitable ranges. Finally decided that chopped chicken viscera found to be ideal food for better growth and survival of catfish Rita rita reared in cemented cisterns.

...
Hafiz Muhammad Arsalan1, Maria Altaf1, Zeemal Seemab Amin1, Muhammad Khalil Ahmad Khan2, Anum Shahzadi1, Hina Mudasser1, Iqra Maqsood1, Nazia Gulshan1, Saira Naseem3
...oncentration of reactive oxygen species can disturb the body’s defense mechanism which cause potential oxidative injury to tissues and lead to cartilage degradation in RA patients.
...
Ju Zhang1,2, Dong-Sheng Jia3, Shi-Hao Zhao1,2, Xiao-Liang Xie3, Hong Chen4 and Hai-Feng Li4,*

 

... by determining reactive oxygen species (ROS) level, paraquat-stress survival rate, malondialdehyde (MDA) content as well as superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) activities.We observed that HGQ exerted little effect on the growth of wild-type N2 nematodes at concentration < 0.6 mg/ml, and 0.05 mg/ml of the HGQ significantly prolonged the lifespan and reduced the lipofuscin level in N2 nematodes. However, the HGQ failed...
Kanwal Nisa1, Sadaf Ashraf1, Masood Ahmed Siddiqui1*,Naila Taj1Habib-Ur-Rehman1, Arifa Bano1 and Naeem Rashid2
...s 9.5, in the absence of oxygen. The specific activities for POR and PDC reactions were 22 U/mg and 3.8 U/mg, respectively. The native enzyme had an apparent molecular weight of 240 kDa and was a dimer of heterotetramers (αβɣδ)2 with molecular masses of 44, 36, 20 and 12 kDa, respectively. Both of the activities were oxygen sensitive. The apparent Km values for POR reaction towa...
Jun Yan Bai1*, Xiao Ping Jia2, Xiao Hong Wu1, Guang Lu Li1, Heng Cao1, Xue Yan Fu1 and Kun Peng Shi1
...up.
...
Fatima Hashim Abbas1,2* and Alaa Tareq Shakir Al-Hassnawi1
...acity (TAC) and reactive oxygen species (ROS) were measured in the serum of all studied groups. MDA levels were significantly higher (p≤0.05) in aborted women with T. gondii compared to negative control. MDA levels were also significantly higher (p≤0.05) among aborted women with Cytomegalo virus compared to negative and positive control groups. All aborted women had significantly higher levels of TAC levels (p≤0.05) compared to the control grou...
Lei Gao1, Gong-xue Jia2, Zheng-yuan Huang1, Ming-xing Yue3, Chao Zhang1, Shi-en Zhu1 and Xiang-wei Fu1,*
...e intracellular reactive oxygen species (ROS) and glutathione (GSH). DNA DSBs were examined by immunostaining of pi-H2AX, the marker of DNA DSBs. The results showed that the GVBD rates were similar in oocytes of young and aged mice. Polar body extrusion was significantly delayed in aged mice (P < 0.05), however the rate of polar body extrusion was similar to that of young mice at 16 h of IVM. Moreover, PN formation of parthenogenetic embryo was significantl...
Xuhui Zhang1, Zhiyuan Sun2, Jinfeng Cai1, Guibin Wang1, Zunling Zhu1, Linguo Zhao3 and Fuliang Cao1,*
...rum and hepatic reactive oxygen species (ROS) in FR groups were significantly decreased compared with the control or NF group at 42 d of age. Furthermore, serum total superoxide dismutase (T-SOD) activity of birds from group FR3 was significantly increased (42d) compared with NF group. Additionally, the expression of antioxidant enzyme genes including nuclear factor erythroid 2-related factor 2 (Nrf2), heme oxygenase 1 ...
Min Lv1, Hui Gan2, Zhide Ruan1, Huizan Yang1, Rui Wang1, Laiba Shafique3, Huma Naz4 and Huawei Ma1,
...th 1.2 m) with dissolved oxygen concentrations above 5.2 ± 0.3 mg/l, and pH 6.5–8.1. Water flow in the ponds was poor. The amount of feed increased from 0.81 ± 0.35 to 13.42 ± 1.89 g/fish-day throughout the experiment. Samples were collected between mid-March and October 2016, and we monitored the Cd, Cr, and Hg concentrations in gills, large intestines, small intestines, intestine
Fehmina Ashraf1*, Muhammad Irfan2, Hafiz Abdullah Shakir1, Shaukat Ali3, Muhammad Khan1
...;">Laccases (p-diphenol: oxygen oxidoreductase, EC 1.10.3.2) are multi-copper polyphenolic oxidases that oxidize many phenolic and non-phenolic aromatic compounds such as amino or methoxy monophenols, syringaldazine, ABTS and amino or methoxy monophenols. They have been depicted in various species of bacteria, plants and in different genera of fungi. Laccases have been purified by various methods. It involves in di-oxygen to...

Daulat Khan1*, Khizar Azam2, Noor Muhammad Khan1, Muhammad Israr1, Naeem Ejaz3 

ASSESSMENT OF WASTEWATER FOR DISPOSAL IN ACCORDANCE WITH NEQS CRITERIA AND ITS REUSE FOR IRRIGATION WITH DILUTION

Shafiullah1*, Mohammad Nafees2 

MUNICIPAL WASTEWATER TREATMENT BY COAGULATION/ FLOCCULATION PROCESSES VIA OPTIMIZATION OF INOCULATION DOSE AND SETTLING TIME
...erved in color, chemical oxygen demand (COD) and turbidity by
96%, 66% and 89%, respectively.

...

Sajjad Haydar*, Zunaira Asif*, A. A. Bhatti**, Obaidullah Nadeem***, Ghulam Hussain*, Nadeem Abbas*

EFFICIENCY OF WASTEWATER TREATMENT PLANT IN THE PUNJAB TANNERY SECTOR: A CASE STUDY OF DADA TANNERY
...S), five day biochemical oxygen
demand (BOD) and chemical oxygen demand (COD), respectively. Whereas, the mean effluent concentrations of
TSS, BOD and COD were 216 mg/L, 199 mg/L and 1023 mg/L, respectively. The effluent from WWTP exceeded the
National Environmental Quality Standards (NEQS) for TSS, BOD and COD. It was due to the low concentration of
Mixed Liquor Suspended Soli...

 Muhammad Nafees*, Asim Nawab*, Wisal Shah**

STUDY ON THE PERFORMANCE OF WASTEWATER TREATMENT PLANT DESIGNED FOR INDUSTRIAL EFFLUENTS
Sinan Uzundumlu1, Yesim Buyukates1,*, Murat Yigit2, Musa Bulut2,  Rıdvan Kaan Gurses1 and Barbaros Celikkol3
...linity, pH and dissolved oxygen, total suspended solids, chlorophyll-a and inorganic nutrients such as NO2+NO3, NH4, PO4 and SiO2 were observed between May 2014 and September 2014 in the study area. The observed results were compared with acceptable limits pronounced in international organizations such as EPA and FAO, and national organizations such as WPCR and RTMAF as well as the previous studies conducted in the r...
Kui Li1, Lijun Li1, Jialun Fu2, Yi He2, Zhaohui Song2, Shuiping Zhou2Luobu Gesang1* and Rui Liu2*
...2.31). Besides, arterial oxygen saturation (SaO2) value for those taking CDDPs was significantly higher than that in the CON group (87.86% vs. 85.72%, P=0.0388) on day 10. These preliminary findings suggested that CDDPs might be regarded as an effective prophylaxis for AMS to a certain extent without any specific adverse effects, relieving clinical manifestations of AMS, especially after rapid ascents (Clinical Trial Registry Number: NCT03270787).

Ghulam Akbar1*, Ali Ahmad2, Neha Arooj1, Muhammad Anjum Zia1, Aamna Rafique1, Sania Riasat1, Mohsin Raza1, Mahpara Qamar1, Shahneela Nusrat1 and Shakila Hanif1

Critical Update for the Treatment of Anemia by using Advanced Genome Editing Crispr Cas Technology
...ls which results lack of oxygen supply towards tissues of body. It is common and worldwide problem that associates with all ages like pregnant women, children and aged people. Anemia associated with numerous infectious and continual problems such as persistent kidney disease, cancer, ischemic heart ailment and inflammatory bowel disorder. However, with the development in generation at genome editing level have made feasible to accurate mutations in human genom...
Xuya Zhou1, Ying Liu1, Deqin Xu1, Jie Bao1, Yaru Cao2 and Yong Jin3*
...litazone, selective cyclooxygenase (COX)-2 inhibitors: rofecoxib, celecoxib. This study was aimed to find out whether unification of two drugs would increase cardiovascular side effects. Type 2 diabetic rat model was induced through feeding with fodder containing high sugar and lipid and intraperitoneal injection of streptozotocin. The adjuvant-induced arthritis model was established by Paraffin/BCG. We used western blot to explore the protein expression level...
Muhammad Tahir Waseem1, Abdul Majid Khan1*, Abdul Ghaffar2, Ayesha Iqbal1 and Rana Manzoor Ahmad1,3
...e analyses of carbon and oxygen of tooth enamel carbonate. A gradual increase in hypsodonty and complexity in plications indicate the drier environments with hard and tough food available during the late Miocene. The late Miocene hipparionines were expected to have inhabited a mosaic of woodland and grassland with predominant C3 vegetation which latter shifted to C3/C4 grasses. For this purpose, fifteen dental samples (Five for...
Alamaary Mohaammed Saad1,3, Abd Wahid Haron1*, Mohamed Ali2
Mark Wen Han Hiew1 and Lawan Adamu1
.... The excessive reactive oxygen species (ROS) and the capacity of the antioxidants could affect the OS level in the frozen semen. This study was to determine the addition of different concentrations of antioxidants to evaluate oxidative stress and fertility of frozen semen in horses. Seven stallion were used for semen collection in this study. A total of twenty ejaculates was collected from three healthy stallions twice a week for the experiments 1 and 2. All ...
Yawang Sun, Yongjiang Wu, Jingbo Chen, Zili Wang, Juncai Chen, You Yang and Guozhong Dong*
...e production of reactive oxygen species increased in a dose-depend manner. Cellular concentrations of oxidative damage markers were positively correlated with applied LPS concentrations. Total antioxidant capability and the activity of superoxide dismutase (SOD) increased with increasing LPS concentrations. Gene expression of antioxidants including SOD, NADPH-quinone oxidoreductase 1, and hemeoxygenase 1 were significantly i...

Saba Aleem1*, Iram Sharif2, Mehvish Tahir3, Muhammad Najeebullah3, Ali Nawaz1, Muhammad Imran Khan1, Amina Batool1 and Waheed Arshad1 

...rly may lead to reactive oxygen species scavenging to protect cell membranes.

...

Rahat Rukhsana1, Shahnaz Rashid2, Asma Fatima2, Owais Iqbal Khan3, Syed Babar Hussain Shah4, Mumtaz Ali4 and Ghulam Abbas2*

...otal hardness, dissolved oxygen (DO), chlorophyll-a and phytoplankton-density during the period from March, 2015 to June, 2016. The chlorophyll-a concentration was determined by using the acetone extraction technique. Ponds water sample (50 liters) was filtered through plankton net of 20 µm pore size and preserved in 4% formaldehyde for the analysis of phytoplankton. Subsequently, the phytoplankton were counted under microscope. Result showed that water ...

Mai A. Kilany1; Hanaa H.A. Gomaa1; Yousry E. Abo El-magd2 and Nermin Raafat2.

...erproduction of reactive oxygen species (ROS) in hepatocytes leading to their proliferation and triggers HCC. Manganese superoxide dismutase (MnSOD) is a nuclear-encoded antioxidant enzyme that neutralizes free radicals. Val16Ala single nucleotide polymorphism (SNP) is one of the most widely investigated SNPs in the MnSOD gene, where C to T transition resulting in the con-version of valine to alanine at amino acid 16 within the mitochondrial signaling se-quenc...
Abeera Razzaq1, Sajid Abdullah1, Huma Naz2*, Khalid Abbas1, Laiba Shafique3 and Qingyou Liu3
...e production of reactive oxygen species (ROS). These ROS can interact with nucleic acids and cause oxidation of DNA. The potential of ROS to damage DNA has become a topic of significant interest for environmental toxicology studies. Thepresent research was conducted to assess the genotoxic potential of cobalt (Co) and chromium (Cr) mixture to fish Labeo rohita by using micronuclei assay. Fish were exposed to the four sub-lethal doses (26.61, 13.30, 19.9...

Aliya Munir1, Sajid Abdullah1*, Huma Naz2*, Khalid Abbas1, Tanveer Ahmed3 and Zahid Farooq2

...g the number of reactive oxygen species. Oxidative stress biomarkers like antioxidants enzymes have been successfully used in ecotoxicology field for evaluating the stress response of organisms exposed to pollutants. Therefore, this work was designed to evaluate the peroxidase (POx) level in kiney, gills and liver of fish Channa striata exposed to LC50 concentration (1.374µgL-1) of deltamethrin+endosulfan (DM+ES) mixture for 4-day. Sampling was performed...

Ghulam Muhiyuddin Kaloi1* and Mehrunisa Memon

... for its high biological oxygen demand, chemical oxygen demand and soluble salts. Its injudicious use may be hazardous for soil health. Study was conducted to evaluate significance of wastewater in context of sugarcane juice quality and soil health. Wastewater was tested on experimental field of Matiari Sugar Mills in a randomized complete block design with factorial combination of five concentrations of wastewater (0, 5, 10...

Muhammad Aftab1*, Aneela Riaz2, Ghulam Sarwar3, Muhammad Arif1, Qudsia Nazir1, Ifra Saleem1, Sarfraz Hussain1, Abid Ali4, Abid Niaz1, Fakhar Mujeeb4, Khalid Mahmood5 and Sarfraz Nawaz6

...oduction of the reactive oxygen species (ROS) including hydroxyl radicals (OH-), hydrogen peroxide (H2O2) and superoxide (O2-). However, on their side, efficient antioxidant defense system developed in plants, which having lower molecular weight of antioxidants. It also reduces (ROS) enzymatic activities including catalase (CAT), peroxidase (POD) and superoxide dismutase (SOD). Under combined stress conditions agronomic, bio-chemical, quality and over all yiel...
Dong-Min Hou1, Ting Jia2, Chun-yan Liu1, Zheng-Kun Wang1 and Wan-Long Zhu1*
...pha; (PPARα), cyclooxygenase 2 (COX-2) and peroxisome proliferator-activated receptor coactivator 1α (PGC-1α) of WAT were measured. The results showed that body mass, food intake and RMR were decreased in T. belangeri under FR condition, and the relative expressions of COX-2 and BMP7 in WAT were also declined. After refeeding, the above indexes were all recovered to the control level. But there were no significant differences between m...
Congfen Zhang1,Yingxiao Liu2, Linfeng He2, Fengjun Shi2, Weitang Yao2 and Xuegang Luo2,*
...d expression of reactive oxygen species (ROS) enzymes can be used as a biomarker for detection of heavy metal contamination.
...
Amr N. El-Shahat1, Refaat G. Hamza1,*, Ashraf M. Mounir1 and Madeha N. Al-Seeni2
...y production of reactive oxygen species (ROS) associated with increase in lipid peroxidation. Graviola fruits have been reported to possess antioxidant and anti-inflammatory activities. The present study was designed to determine the possible protective effects of graviola fruit juice (GFJ) against radiation induced oxidative stress and biochemical alterations in the liver and kidney of male albino rats.In the present study, gamma- irradiation (2 Gy every 3 da...

Nuzhat Naseem, Sajid Abdullah and Sana Aziz*

...amined e.g pH, Dissolved oxygen and temprature. Results were examined by Tukey’s Honestly Significant Difference Test. Phytase supplementation decreased the moisture content and increased the crude ash, protein and fat significantly in proximate composition of whole-body of the fish and hence, improved the meat quality of Labeo rohita fingerlings.

...
Ilvir Khabibullin1*, Ruzel Khabibullin1, Irina Mironova1, Lyalya Musina2, Elmira Akhmadullina1, Victoria Morozova1 
...body systems that ensure oxygen delivery to the working muscles.
 
Keywords | Adaptation, Adsorbed drone brood, Lemongrass seed tincture, Male hamsters, May chang tincture, Mice, Pantocrine tincture, Physical load
...

Mohammad Mahmudi1,2*, Muhammad Musa1,2, Sulastri Arsad1,2, Evellin Dewi Lusiana1,2, Alamanda Bunga1, Nur Azlina Wati1 

...emperature and dissolved oxygen. Therefore, the study indicated that the existence of mangrove was supporting to increase the quality of water supply for the cultivation as well as the aquaculture water sewage in terms of phytoplankton bioindicator.

Keywords | Bioindicator; Coastal ecosystem; Integrated mangrove aquaculture; Aquaculture sustainability; Shrimp farming 

...

Uzma Jabeen1, Asmat Salim2*, Irfan Khan2, Nadia Naeem3 and Rubina Mushtaq4

...peutic drug. As reactive oxygen species are significant regulators of transcription factors and gene expression, this study was aimed at analyzing the expression levels of genes that are induced in response to oxidative stress following DOX administration to rats. DOX was administered to rats intraperitoneally at 3 mg/kg at alternate days for two weeks. Kidney tissues were harvested and the mRNA levels of glutathione peroxidase-1(Gpx1), NAD(P)H quinone dehydro...

Xian Zhang1, Erjiang Lin1, Shizhe Hong1 and Zhengjie Zhu2*

...SSAT, and cultured at 1% oxygen concentration. Western blotting was used to detect expression of SSAT, Akt, GSK-3β and β-catenin proteins; and flow cytometry was used to detect cell apoptosis rate and mortality rate. SSAT was successfully transferred into prostate cancer LNCaP cells. Compared to the blank cell group and the blank vector group, the expression of Akt, GSK-3β and β-catenin proteins in the SSAT transfection group was significan...

Ahmad Ali1, Zaib Ullah2, Muhammad Javaid Asad1*, Muhammad Rafi3, Muhammad Maqsood4 and Sajid Mahmood5,6

...y underneath outstanding oxygen circumstances becomes quantified by the utilization of the equivalent vintage check. Photodynamic therapy is developing as a potential solution for masses malignancies. The purpose of this task changed into to find the reasonable total of acknowledgment of photosensitizer as medication and portion of laser moderate which may likewise also in addition additionally reason most extreme harmful cell absence of ways of life in vitro ...
Aiman Al Mufarji1, Abd El-Nasser Ahmed Mohammed1*, Rashid Al Zeidi2, Haitham Al Masruri3
... and partial pressure of oxygen (SPO2) were recorded, as well as, blood samples were collected and analyzed for hematological parameters and plasma biochemistry parameters. The results indicated that heat stress negatively influenced the thermo-tolerance, hematological, and plasma biochemistry parameters. M. oleifera alleviated the negative effects of heat stress, as well as modulated thermo-tolerance responses, metabolites, and liver and kidney functions. M. ...

Shambel Boki Dabi

... water pH, and dissolved oxygen were measured directly on site. A simple test kit was used to evaluate nitrite and ammonia levels. The result revealed a high level of alkalinity (66.3±39. 1mg. L-1) at downstream and lowest concentration (58±40mg.L-1) was found in the middle stream. The upper stream has a high CO2 concentration (14±3.6mg.L-1) while the middle stream has a low CO2 concentration (9.4±0.77mg.L-1). The maximum chloride c...

Asma Fatima*, Ghulam Abbas and Shahnaz Rashid

...mperature, pH, dissolved oxygen, salinity, transparency, ammonia, phosphates, nitrates, potassium, calcium, total alkalinity and total hardness were determined. Overall, 61 species of plankton have been recorded from the studied ponds and categorized into 19 groups; of which 25 phytoplankton species belonged to four major groups, whereas, 36 zooplankton species belonged to 15 groups. Among them, Bacillariophyta (69.815%) and copepods (78.927%) were “most...

Muhammad Akram1*, Muhammad Imtiaz Shafiq2, Amber Malik3, Farmanullah Khan4, Munir Ahmad Bhinder5 and Muhammad Sajjad6

...GST neutralizes reactive oxygen species to regulate physical homeostasis in the body. The target of this study was to evaluate the molecular role of GST genotypic polymorphism involved in the development of CVD. For this case-control study, a total of 504 participants including 261 CVD patients and 243 healthy individuals were enrolled after taking informed consent. The analysis of the three allelic variants GSTM1, GSTT1, and GSTP1 was carried out through PCR-...

Muhammad Hanif Chandio1,2*, Naeem Tariq Narejo2, Muhammad Farooq Hassan3, Faheem Sadar4, Nasiruddin Shaikh1, Bushra Ainy Dars5, Ghulam Abass6, Asma Fatima6 and Shahnaz Rashid6

...30.6oC, pH (7.3 to 7.5), oxygen (4.0 to 4.8mg/l), alkalinity (149 to 180mh/l), nitrate (0.17 to 0.18mg/l) and ammonia from 0.35 to 0.55ug/dLumol/litre. Theresults of the current study concluded that Channa punctatus have a preference to living in a small community than large schooling and could be reared 10/fish/m2 was found to be suitable density for growth and survival in cemented cisterns. Present study plays an important role for culturing and rearing of n...

Zaidi Zona, Zulfiqar Ali*, Rida Ahmad and Irfan Zainab

...re 15.9°C, dissolved oxygen (DO) 6.41 mg/L, Total Dissolved Solids (TDS) 125.62 mg/L total hardness 77.50 mg/L, alkalinity 72.17 mg/L (as CaCO3) and conductivity 129.04 µs/cm. Planktonic study revealed the presence of variety of phytoplankton (n=31) and zooplankton (n=3) species in study area. In total, 37 fish species were found in the study area, with species richness rising from zone one (n =10) to zone five (n =33). Altogether, the fish diversity...

Qamar Javed Iqbal1*, Zainab Masood2, Asad Abbas3 and Sidra Munir4

...y 30% H2O2 which acts as oxygen donor and glacial acetic acid which acts as oxygen carrier using inert solvent (benzene) in the presence of acidic ion exchange resin (Amberlite IR-120) as catalyst. The effect of different parameters such as catalyst loading, temperature, stirring speed, molar ratios of H2O2 and acetic acid to ethylenic unsaturated double bond were studied. It was found that maximum Relative epoxy yield (REY)...

Hasnain Raza1*, Tanveer-ul-Haq1, Muhammad Imran1, Nabeel Ahmad Ikram2 and Muhammad Bilal Shoukat1

...ers including biological oxygen demand (BOD), chemical oxygen demand (COD), pH, electrical conductivity (EC), total solids (TS), total suspended solids (TSS), total dissolved solids (TDS), sodium (Na), calcium (Ca), potassium (K), magnesium (Mg), residual sodium carbonates (RSC), sodium adsorption ratio (SAR), carbonates (CO3), and bicarbonates (HCO3) by using standard analytical procedures. The contamination in the wastewat...

Mingqing Wang1 and Xiaojuan Chen2,*

...ters including pH value, oxygen partial pressure (PaO2) and carbon dioxide partial pressure (PaCO2) were compared. We found that respiratory stimulant combined with different doses of glucocorticoid methylprednisolone positively improve the pH value of patients with acidosis, increase the partial pressure of oxygen and lower the partial pressure of carbon dioxide (P<0.05 in all three groups). Methylprednisolone at 40mg ev...

Lei Zeng1,2,3,4, Pimao Chen1,2,3,4, Zhenzhao Tang1,3,4, Jie Yu1,2,3,4 and Guobao Chen1,2,3,4*

...ely related to dissolved oxygen (DO), water transparency (Tra) and total inorganic nitrogen (TIN). The findings in this paper are significant for the protection and restoration of crustaceans resourcs along coastal water, given the rapid establish of AR around the world.

...

Hongfeng Guo

...ttent hypoxia model: the oxygen concentration in the cabin of mice in intermittent hypoxia group was maintained at 40%, then decreased to 10% and maintained for 3 min. After that, it was continuously increased to 40%, and was decreased to hypoxia after 8 min. The operation was repeated 3 times every 3h. The drug administration group was treated with continuous CPAP during modeling. The expressions of malondialdehyde (MDA), superoxide dismutase (SOD) and prosta...

Monu Karki, Amit Kumar and Gnanavel Venkatesan*

... enhancing nutrients and oxygen supply (vascular endothelial growth factor), ORFV possesses several unique strategies, to fight against host immune environment. Some of the genes have been acquired from the host and some are flowing through the family and genus evolving with the virus to adapt and efficiently set up an infection in immune-loaded host cells. This review focuses on the important virulence genes of the orf virus and their functions with recent ad...

Yanjie Liu

...to control group (normal oxygen group), hypoxia group, and high-altitude group. Each group was given the same exercise intensity. Venous blood was collected before and after each test to determine changes in Immunoglobulin A (IgA), immunoglobulin G (IgG), immunoglobulin M (IgM), IL-2, WBC, natural killer (NK) cell activity, C3, C4, CH50 and body weight. We found that the levels of IgA, IgG, and IgM in the three groups decreased; while IL-2 levels increased, an...

Tariq H.Y. Al-Maliky*, Mahmood S. Hashim and Amal S. Al-Sheraa

...idity 7-8, and dissolved oxygen 5-10 g.L-1. Bacterial contamination (CFU m.L-1 10⁶) was evident in treatment D and included four types of bacteria: Bacillus spp., Escherchia coli, Staphylococcus spp., Streptococcus spp., and Enterococcus spp. The survival rates of M. affinis during different breeding periods in the two salinities remained as follows: (93.33 ± 5.77, 9.00 ± 10.00, 83.33 ± 5.77 %) and (93.33 ± 5.77, 90.00 ± 10...

Nasratullah Baloch1*, Naeem Tariq Narejo2, Hamida Narejo3, Muhammad Farooq Hassan4, Muhammad Hanif Chandio5, Faheem Saddar6, Dharti Shahnawaz Thebo7, Ghulam Abbas8 and Shahnaz Rashid8

...ure, salinity, dissolved oxygen, and transparency were taken into account twice in a month from sampling area during the whole period of research. The temperature found to be varied from 21-35.7oC, pH8.0-8.1, DO 3.57–5.0 mg/l, salinity 34.2-39.9 mg/l and transparency 38.5-53.0 µS/cm. Lastly it was resolved that the atmosphere of Sonmiani bay found to be supportive for the aquatic biota (zoo and phytoplankton) which in turn conducive for the rearing...

MARIUM ASLAM, MUHAMMAD JAVED, FAIZA AMBREEN* & FARIHA LATIF

...defense against reactive oxygen species (ROS) and other free radicals. When the rate of ROS exceeds the capacity of antioxidant enzymes, non-detoxified radicals begin to attack the bio-molecules. Therefore, present research work was planned to study the effect of zinc on the peroxidase activity in the liver and kidney of Catla catla. To check the concentration based effect, C. catla were exposed, separately, to 96-hr LC50 of zinc and its sub-lethal concentrati...

Yuhua Chen1 and Song Lu2*

...(P<0.05). The rate of oxygen consumption and extracellular acidification of CD8 + T cells increased after electric in stimulation group compared with the control group (P<0.05). To conclude, that electroacupuncture and transcutaneous electrical acupoint stimulation could inhibit the occurrence of tumors, promote proliferation and activation of T cells, and strengthen the immune clearance of tumor cells.

...

Muhammad Asim Bhutta1,2*, Amna Bibi2, Nadia Hussain Ahmad2, Sadia Kanwal2, Zarmeena Amjad1, Hafeez ur Rehman3, Umar Farooq3, Muhammad Nouman Khalid4 and Syeda Fiza Nayab5

...verabundance of reactive oxygen species (ROS). Reactive oxygen species such as H2O2 and O2, that develops in photosystem II as a result of exposure to intense light, start to damage electron transfer system components and protein structure. Plants have adapted several protective mechanisms like production of antioxidants, enzymes and carotenoids to face reactive oxygen species and avoid ph...

Lianci He1, Dingxi Bai2, Chenxi Wu2, Yizhu Zhong2, Shi Chen2, Xinru Bao2, Jing Gao2*, Chaoming Hou2*

... NF-κBp65 and cyclooxygenase-2 in the serum were measured. Compared with the CON group, the CFS group had decreased weight and decreased activity and mobility (P < 0.05). Compared with the CFS group, the three SXC groups and the FLU group all had varying levels of increased body weight, horizontal motion, vertical motion and fatigue time (P < 0.05). The SXC downregulated the mRNA and/or protein expression of IL-1β, TNF-α, TAK1, TAB, IKK&...

Yakun Ge

...m cells through reactive oxygen species (ROS). A2780 cell line was purchased from the American Type Culture Collection and cultured in RPMI-1640 medium supplemented with 10% fetal bovine serum, 50μunits/mL penicillin and 50μg/mL streptomycin, maintained at 37°C and 5% CO2 in a humid incubator environment. Quantitative analysis of ROS was performed using flow cytometry and median fluorescence intensity detection. Cell proliferation was detected by MTT...

Weijun Chen1*, Shiyang Gao1, Ping Sun1, Xiaohui Sun2, Yongbin Wei1, Jingyang Chen1 and Jialong Chen1

...factor 2 (Nrf2) and heme oxygenase-1 (HO-1), and simultaneously increased the mRNA expression of tumor necrosis factor α (TNF-α), interleukin-1β (IL-1β), and IL-6 in liver of common carp compared to control diet (P<0.05). However, diet NaBT significantly improved fish liver health by decreasing contents of TCHO and MDA, down-regulating mRNA expression of pro-inflammatory cytokines (e.g., TNF-α, IL-1β and IL-6), increasing th...

Hafiz Muhammad Arsalan1, Amina Arif1 and Muhammad Khalil Ahmad Khan2*

...stem, increased reactive oxygen species (ROS) production in response to antioxidant (AOX) defense systems lead to oxidative stress (OS). Our study aimed at biochemical profiling of CML patients in response to imatinib or nilotinib therapeutic drugs. Fresh venous blood sample (10 mL) of 170 CML diagnosed patients and 10 healthy individuals was collected in heparin vial from oncology department, Mayo hospital and Jinnah hospital Lahore, Pakistan. Biochemical pro...

Nida Sadaqat1, Sheheyar Ahmed Khan1, Amna Bibi1, Sadaf Zahra1, Muhammad faisal Salamt1, Noreen Latief2 and Fatima Ali1*

...ators including reactive oxygen and nitrogen species (ROS, RNS), which are implicated in pathophysiological events in burn patients. Excessive productions of free radicals are harmful and implicated in tissue damage and multiple organ failure. Supplementation of antioxidants has proven beneficial in decreasing free radicals in burns. The aim of the present study was to investigate the effect of N-acetyl cysteine (NAC) on biochemical alterations during the post...

Salma Jameel Askar 

...ugs, suppression of cyclooxygenase (COX-1) activity by these drugs has been associated with substantial side effects, beetroots act as a medicinal herb in the treatment of hematological disorders, and act as antioxidant. The aim of this study was to examine the effects of sub-chronic exposure to meloxicam, nonsteroidal anti-inflammatory drug, on hematological alterations and liver functions parameters in albino male rats and to determine the effects of Beetroo...

ZAHOOR AHMAD SAJID1* & SHEZA AYAZ KHILJI2

...eutralizing the reactive oxygen species produced during salt stress episode. It is therefore, suggested from the results of this research work that biochemical characteristics were related to a transferring of plants from being salt sensitive to relatively more tolerant. Apparently lot of work on this salt bush regarding biochemical and physiological characteristics still remains elusive and needs further experimentation under greenhouse as well as field condi...

Naeem Tariq Narejo1*, Muhammad Hanif Chandio2, Faheem Saddar3, Majida Parveen Narejo4, Bushra Ainy Dars5, Hafeez ur Rehman Narejo6, Athar Mustafa Laghari2, Shafiq ur Rehman Shaikh3, Shahnaz Rashid7 and Ghulam Abbas7

...bited a higher dissolved oxygen (DO) concentration in T-II, measuring at 5.6 mg/l. Conversely, the month of April recorded a minimum DO concentration in T-III group, measuring at 3.6 mg/l. The study determined that the feed with a protein content of 40% was suitable for promoting the growth efficiency of Oreochromis niloticus when grown in glass aquaria. 

...

Ying Chen1, Chao-Zheng Li2, Zhun Yu3, Jia Zhou4, Yan Xu4, Zhe Lin4, He Lin4* and Xiao-Wei Huang4*

...ed factor 2 (Nrf2), heme oxygenase-1 (HO-1), and NADH quinone oxidoreductase 1 (NQO1) in rat myocardial tissue. In the results, ECG showed that the MIRI model was successfully established; VAP can significantly reduce the activities of LDH, CK-MB in serum of rats, increase the activities of SOD, GSH-Px, CAT in myocardial tissue, reduce the activity of MDA in myocardial tissue, reduce interstitial edema and inflammatory infiltration, and improve the structural ...

Shu-Zhi Qin, Wen-Pei Ling, Mei-Fang Yin, Chun-Yu Luo and Cheng-Guo Zhao*

...florin (PF) on hypoxia reoxygenation (H/R) injury and its effect on MAPK signal pathway to reveal the mechanism of PF against myocardial ischemia-reperfusion injury, in this study, the H/R model of H9C2 cells was established by hypoxia for 3 h and reoxygenation for 3 h. H9C2 cells were divided into 4 groups, the control, PF + control group, H/R group and H/R + PF group. The activities of aspartate aminotransferase (AST) and ...

Dan Song1,2, Ming-Juan Ge3, Jie Li1,2, Yi Jiang1, Xiu-Mei Kong1, Jiao-Jiao Xu1, Xu Ji1,2, Rui-Xin Shi1 and Qin Zhao1,2*

Ghusoon Hasan Jadaan1*, Khalisa K. Khudair2 

...n carbonyl(PC), reactive oxygen species (ROS), and gamma-glutamyl transferase concentration(GGT). The results indicated that 200 mg/kg of SiO2 - NPs orally for 4 weeks contributed to a substantial drop in serum TAC-O, an increase in MDA, GGT, PC, and ROS concentration, and attenuation of silica’s oxidative stress status, CP NPs (T3) or SiO2 NPs (T2) administered orally to female rats for four weeks constitutes a case of oxidative stress. The study reveal...
Rehan Ahmed Siddiqui1,2*, Shabana Usman Simjee2,3, Nurul Kabir4, Muhammad Ateeq3,5, Kevin Joseph Jerome Borges6, Muhammad Raza Shah3 and Rahman M. Hafizur2
...istry for actin and cyclooxygenase-2 (COX-2) were also carried out. Real time RT-PCR studies were performed to check mRNA expressions of nuclear factor-κB (NFκB) p50, inducible nitric oxide synthase (iNOS), kidney injury molecule-1 (Kim-1) and hemeoxygenase-1 (HO-1). CA and CA-AuNPs improved blood urea and creatinine levels when compared with the glycerol induced AKI group. The compounds kept the actin intact, de...

Taleeha Roheen1, Shagufta Kamal1*, Shazia Anwer Bukhari1, Ghulam Mustafa1 and Saima Rehman2

... and soluble methane monooxygenase (sMMO) producing methanotrophic bacteria from rice paddy soil of different regions of Punjab, Pakistan were studied using phylogenetic analysis. Morphological and biochemical analysis showing the presence of different species of novel methanogenic archaea and sMMO-producing methanotrophic bacteria in rice paddy soil samples. The evolutionary analysis indicated a phylogram with five monophyletic groups (MPG-I to MPG-V). Result...

Moazama Batool1*, Saima Naz2*, Sheeza Bano1, Sadia Nazir3, Ghulam Abbas4, Ahmad Manan Mustafa Chatha5, Maria Lateef2 and Fatima Yasmin2

...lished between dissolved oxygen levels and both fish species in the test environment. These findings contribute to understanding the differential responses of Catla catla and Labeo rohita to the toxic effects of lead, nickel, and cadmium mixture.

...

Abeer Alahmari1,2*

...y by scavenging reactive oxygen species (ROS) and relieving oxidative stress as a result of its rich chemical content of furano-sesquiterpenes, which possess powerful antioxidant activities.

...

Pakistan Journal of Zoology

April

Pakistan J. Zool., Vol. 56, Iss. 2, pp. 503-1000

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