Muhammad Mushtaq, Umer Sadique, Naila Chand, Iftikhar Ahmed, Said Sajjad Ali Shah, Ijaz Ahmad, Imran Ullah and Muqadar Shah

...caused by high fat diet, obesity and diabetes.Hypolipidemic and hypoglycemic effect of water based infusion of Withania somnifera was investigated in broiler chicks. One hundred and twenty (120) day-old broiler’s chicks were alienated into four treatment groups namely WST-0, WST-I, WST-II and WST-III with three replication. Group WST-0 was kept as a control, while WST-I, WST-II and WST-III were treated with W. somnifera water based infusion @ 10, 20 and ...
Farah Ashfaq* and Tasnim Farasat
...and metabolic markers of obesity in young Pakistani subjects.
...
Muhammad Saqlain1, Humaira Kalsoom1, Muhammad Fiaz1,2, Abid Mahmood1, Rizwan Aziz Qazi4 ,Waseem Safdar5, Pakeeza Arzoo Shaiq1,Bernard M.Y. Cheung3 and Ghazala Kaukab Raja1,*
... for insulin resistance, obesity, diabetes, and metabolic syndrome (MetS). In this study the association of Ala54Thr polymorphism with MetS and its risk components was studied in a local Pakistani population. MetS subjects and controls were recruited from out-patient departments of Pakistani hospitals. Ala54Thr genotyping of 200 MetS patients and 200 healthy controls was performed using a PCR-RFLP. Genotype and allele frequencies were calculated and computed f...

Mian Sajjad Ahmad1, Somia Iqtadar1, Sami Ullah Mumtaz1*, Zafar Niaz1, Iqra Waheed2 and Sajid Abaidullah

...ould be taken to control obesity

...
Ambreen Asghar, Tasleem Akhtar, Nadeem Sheikh*
...etabolic disturbance and obesity. Despite the genetic regulation of metabolic responses, a close relationship between high energy food-intake and increased body-weight has been reported to support several pathologies in the metabolic and immune system. Present work was designed to evaluate the variations in serum protein level induced by fat rich diet. For this purpose, two groups of Wister rats were fed with diets carrying difference in percentage of fats. Pr...
Rana Khurram Aftab1*, Farhat Ijaz2, Samia Jawed3
...The relationship between obesity and hypertension has long been recognized. Overweight and obesity are disorders of balance of energy affecting people of various ethnic groups, age and socio–economic statuses. It has been found that obesity is closely associated and correlated with hypertension. Preventive strategies for obesity may offer a cost-ef...
Farhat Ijaz1, Rana Khurram Aftab2*, Samia Jawed3
...tion of TNF-α with obesity induced IR and T2DM is unclear as results obtained from different studies are very controversial.
Objective: This study was designed to compare TNF-α levels and insulin resistance in obese and non-obese type 2 diabetics.
Methodology: A cross sectional comparative study was conducted in diabetic clinic of Mayo Hospital, Lahore. We determined and compared TNF-α levels and insulin ...
Muhammad Younus1*, Sabah Usman2 and Samia Jawed3
Iqra Arooj1,* and Shahida Hasnain2
...isk factors are smoking, obesity, diabetes, family history, high blood pressure etc. Previous genome wide association studies have identified association of large number of loci with risk of CHD in different populations. The purpose of this study was to determine the association of 6q25.1/rs6922269 and 9p21.3/rs1333049 loci with risk of CHD in a population of Punjab province of Pakistan. A total of 645 subjects were included in this study of which 435 were pat...
Shabana*, Saleem Ullah Shahid and Shahida Hasnain
...for HDL, which is low in obesity. The anthropometric traits were significantly different between dyslipidemic obese subjects and nondyslipidemic non obese subjects. In conclusion, obesity is accompanied by a dyslipidemic profile and increased weight and/or BMI. The progression of clinical forms of obesity can be assessed by the strong predicting indices, including weight, BMI, low HDL and ...

 Mian Azhar Ahmad1†*, Nawab Mohammad Khan2, Asmatullah3

Anatomical variations of hepatobiliary triangle in patients operated laparoscopically for gallbladder diseases from Lahore and Sahiwal
... acute cholecystitis and obesity were subjected to Laparoscopic cholecystectomy. Patients’ age was between 18-70 years, gender ratio was 1:3.5 with female dominance, mean operative time 99.6 minutes and patients remained admitted for 1–3days. The procedure was performed successfully in 91% of the cases. In 09% cases, a conversion to standard open cholecystectomy was necessary; the most common cause was unclear anatomy. Laparoscopic cholecystectomy...
Syeda Ain-ul-Batool1, Sadia1, Kathrin Blasius2,3,4, Angela Kaindl2,3,4 and Ghazanfar Ali1,*
...strophy, eyes exotropia, obesity, polydactyly, hypogonadism, and renal abnormalities. Few additional features of BBS also include delayed motor development, clumsiness, anosomia, ataxia, hypodontia, hearing impairment, hirschsprung disease, cardiovascular and liver disorders. So far 21 genes are reported that cause BBS (BBS1-BBS21). A consanguineous family having clinical symptoms of BBS9 is described in current study. Mutation was detected in BBS9 on chromoso...
Hong Zhang1, Shu-Fen Han2, Jing Wang1, Shao-Kang Wang1, Gui-Ju Sun1 and  Cheng-Kai Zhai1, *
...cholesterol diet-induced obesity and lipid accumulation in rats and the possible molecular mechanisms, 40 male Sprague-Dawley rats were randomly assigned to four different diets, including reference chow diet (RCD), high fat and cholesterol diet (HFCD), city diet (CD) and compound whole-grain diet (CWD). Serum lipid profiles and glucose level were examined after 8 weeks. The molecular mechanisms underlined the effects of CWD on lipid metabolism were investigat...
Rabia Khalid1, Saleema Bashir Shams1, Bibi Nazia Murtaza1,*, Gaitee Joshua1, Saira Mushtaq1, Hassan Al-Talhi2 and Abdulaziz Al-Amri2
...employees, prevalence of obesity was 67.53% and in general population it was 57.1%. The mean values of body mass index (BMI) for bank employees and control population was 24.10± 0.5 kg/m2 and 20.43±1.0 kg/m2, respectively. Analysis of the components of metabolic syndrome demonstrate an abnormal level of low density lipoproteins (LDL) 24.4% and 17.5%, total cholesterol 15% and 7.8%, triglycerides 17.35% and 8.8%, fasting bloo...

Pakistan Journal of Zoology

December

Vol. 51, Iss. 6, Pages 1999-2399

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