Giselle R.R. Ayres* and Brandão P.E
...CoV) belongs to the Gammacoronavirus genus from the Coronaviridae family and Nidovirales order. Coronaviruses have a single-stranded positive RNA genome, corresponding to the largest known RNA genome, with about 27kb for AvCoV. The first 5’ two thirds of this genome, correspondent to a wide ORF1 (also called replicase gene), code for non-structural proteins (nsps) that are enrolled i...
Jixue Hou1,2, Xueling Chen3, Jing Wang4, Hongwei Zhang2, Yu Xi2, Jie Xia2, Xinyu Peng2,* and Xiangwei Wu2,5*
...ercutaneous transluminal coronary angioplasty (PTCA) as well as translational approaches. In this Experiment, we established a unique murine model of femoral artery injury through a home-made wire. The mouse model of vascular injury may be used to explore the molecular mechanism of post-angioplasty restenosis with lowest costing....
Sung Kwon Park1a, Jin Young Jeong2a, Eun Seok Cho3, Yong Dae Jeong3 and Chang Seok Park4*
... triggered by pathogenic coronavirus causing watery diarrhea and high mortality in piglets. This post-viral syndrome results in severe economic losses in the pig industry. However, limited information on the porcine epidemic diarrhea virus-infected pigs is available. Thus, the objective of this study was to identify transcriptomes with RNA sequencing (RNA-seq) in peripheral blood mononucleated cell (PBMC) of piglets, Large White x Landrace crossbreds, infected...
Carolina Torres Alejo1,2, Laila Andreia Rodrigues Beserra1,2, Paulo Eduardo Brandão1,2, Luis Ramiro Luna Espinoza1,2 and Fabio Gregori1,2*
...VA, RVD, and RVF), avian coronavirus (ACoV), and avian astrovirus (AAstV), using PCR reactions followed by nucleotide sequencing and analysis. Twenty-nine pools (29/59; 49%) appeared positive for AAstV, 6 pools (6/59; 10%) were positive for RVD, forty-three pools (43/59; 72.8%) were positive for ACoV, and twenty-four pools (24/59; 40.67%) presented concomitant viral infections of two or three investigated agents. The relative high frequency of occurrence of th...
Mohsan Ullah Goraya1,2, Liaqat Ali1,2 and Iqra Younis3
...cluding influenza virus, coronaviruses and herpes viruses are important pathogens that cause significant losses in the poultry industry. However, successful establishment of infection in the respiratory tract switch on the pathogen recognition by innate immune receptors and establish first line of defense against viral infections. When specific cellular receptors recognize a virus they trigger the translation of inflammatory cytokine and chemokines leading to ...
Iracema Nunes de Barros1,2, Luciane Dubina Pinto3, Rosely Bianca dos Santos Kuroda1, Sheila Oliveira de Souza Silva1, Leonardo José Richtzenhain1,2, Cláudio Wageck Canal3 and Paulo Eduardo Brandão1,2*
...caused chiefly by canine coronavirus (CCoV) and canine parvovirus (CPV). While, CPV is considered the most important cause of diarrhea, studies have shown an increasing prevalence and importance of CCoV around the world. Fatal CCoV infections have been described, however, there is limited information on the molecular diversity of CCoV in many parts of the world. In this study, canine fecal samples from diverse States of Brazil were screened by PCRs for CCoV an...
Ashraf Sayed Awaad1 and Mohamed Zaki Fathy2*
...raphed and compared with coronal and sagittal sections of CT images. While transverse and parasagittal US were performed in goats over the selected new site (last inter-lumber space (L5-L6). The latter was compared with the L6-S space by gross anatomy, CT and image analysis. The results showed wider lumen of the vertebral canal at L5- L6 and the space between the inner part of the vertebrae and the spinal cord is wider than those at the level of L6- S. Moreove...
Iqra Arooj1,* and Shahida Hasnain2
...ascular diseases such as coronary heart disease (CHD) are a growing health concern in developing and under-developed countries. Some of their risk factors are smoking, obesity, diabetes, family history, high blood pressure etc. Previous genome wide association studies have identified association of large number of loci with risk of CHD in different populations. The purpose of this study was to determine the association of 6q25.1/rs6922269 and 9p21.3/rs1333049 ...
Manzoor Hussain1, Muhammad Awais2, Farhatullah3, Saiqa Bibi1, Muhammad Rameez Khan3, Afifa Khalid1 and Sajid Ali3*
Imad Hassan1, Bilal-ur-Rehman2, Muhammad Amir2, Faheem Ali2*, Salman Ilahi2 and Amjad Ali3
...ts stability due to back corona effect. The filtration system proposed in this paper shows the ability of an efficient tool for controlling the flow of particulate pollutant matter from biomass combustion under particular conditions.
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Zeeshan Ahmad Bhutta1,2*, Muhammad Fakhar-e-Alam Kulyar3*, Muhammad Shoaib4, Wangyuan Yao3, Muhammad Asif5, Shah Nawaz6, Moazam Ali7 and Ayesha Kanwal8
Exploratory Study on the Psychological Impact of COVD-19 on Students
...e strike of severe novel coronavirus outbreak (COVID-19) on domestic students who were at high risk of exposure. A cross sectional study was conducted through a semi structured questionnaire. Recruitment of participants was done from different universities of Pakistan. The results showed that the students are more concerned about their family members (p=0.00). Under this influence they have increased the frequency of handwashing and use masks when they have to...
Md. Sahidur Rahman
Origin and Spillover of Coronaviruses: Prospects of One Health Action
...t as a reservoir of alphacoronavirus and betacoronavirus whereas, gamacoronavirus and deltacoronavirus originate in avian species. Domestic animals also play a critical role in disease transmission as they are found seropositive against different coronaviruses. At least seven coronav...
Mardan Aghabey Turghan1, Roller MaMing1*, Li Weidong2, Di Jie1 and Xu Guohua1
...Warbler (Phylloscopus coronatus), Blue-cheeked Bee-eater (Merops persicus), Robin Accentor (Prunella rubeculoides), Tibetan Rosefinch (Carpodacus roborowskii) and Japanese Sparrowhawk (Accipiter gularis) are being reported for the first time from Xinjiang. Among them, Blue-cheeked Bee-eater is reported from China for the first time.
...
Muhammad Akram Muneer1, Khalid Munir1, Ghulam Abbas1’*, Isra Munir1, Mumtaz Ahmad Khan1, Asif Iqbal1, Munsoor ud Din Ahmad1, Muhammad Arshad Javid2, Zareen Fatima1 and Maria Arshad1
...e EastRespiratorySyndromecoronavirus(MERS-CoV)emerged as very importantissuesduringlastthree decadesas these infectionscaused quitelargenumberofhumandeathsworldwide.Coronavirusesaresingle-strandedpositive sense RNA viruses which mainly in past were considered responsible for high percentage of (around 30%) of common cold/flu cases. Viruses causing SARS, MERS and COVID-19 are members of family Coro...
