Tania A. Shakoori1,*, Soumble Zulfiqar2, Khadija Irfan Khawaja3 and Faisal Masud4
...s and metabolism. Sodium butyrate (NaB) is a product of healthy gut microbiota and a histone deacetylase inhibitor. Recent studies have shown that NaB activates the intracellular pathways involving key metabolic regulator molecules. However, the effect of NaB on Sirt1/AMPK and Akt/mTOR axes is not reported. We compared genetic expression of Sirt1, AMPK, Akt, and mTOR in adipose tissue from mice treated with NaB versus placebo. Four groups of mice (n=27) mice w...
Tehmina Aslam, Shagufta Saeed*, Muhammed Tayyab, Huma Mujahid, Ali Raza Awan, Sehrish Firyal and AbuSaeed Hashmi
... synthesis of polyhydroxybutyrate (PHB) by Azotobacter vinelandii. The optimization of different carbon sources and various physical parameters was also performed. Highest yield of PHB was obtained by fermentation of 4% (w/v) wheat bran after 48 h of incubation with 4% (v/v) inoculum volume at pH 7.0 and 37oC. Among different nitrogen sources tested, 0.2% peptone gave the better yield (285 mg/100 mL), while yeast extract decreased the amount ...
Muhammad Naeem1,2, Nasir Rajput1,2, Sher Ali3, Asmatullah Kaka2, Dildar Hussain Kalhoro2, Mehvish Rajput2 and Tian Wang1,*
...oncentration of acetate, butyrate and iso-butyrate were almost similar in TRS-II, AH and CWR; valeric and iso-valericwere lower (P<0.05) in CWR and TRS-I than AH and TRS-II, while the propionate and total VFA were higher in AH but similar in CWR and treated rice straw. The in vitro degradibility of DM, OM and NDF were significantly higher for AH and TRS-II while, ADF was higher for AH. Steam treated s...
Modification of In Vitro Methanogenesis and Rumen Fermentation by using Lauric Acid: A Meta Analysis
Ayu Cusiayuni1, Risan Khaerani Nurfatahillah1, Rakhmad Perkasa Harahap2, Komang Gede Wiryawan3, Dwierra Evvyernie3, Anuraga Jayanegara3*
... acetate, propionate and butyrate, but tended to decrease ammonia concentration (P < 0.1). Lauric acid also reduced dry matter digestibility (P < 0.05). It is concluded that lauric acid is an effective agent for mitigating methanogenesis in the rumen.
Keywords | Lauric acid, Meta-analysis, Methane, Rumen
...
Mengxue Sun1, Yanjiao Li1,2, Zhen Gao1, Qinghua Qiu1,2*, Xianghui Zhao1,2, Lanjiao Xu1,2, Huan Liang1,2, Ke Pan, Mingren Qu and Kehui Ouyang1,2*
...acetate, propionate, and butyrate). All the cell viability in low pH treatment declined more than 50% for 12 h stimulation, and cells treated with low pH for 12 h was selected to be optimal ruminal acidosis model. Cells were then cultured with niacin (0, 20, 40, 80, 160, or 320 mM) for 12 h before, concurrent, and after 12 h treatment with low pH. Results showed that, 1) Pre-treatment protection of niacin: pre-treatment with 20 or 40 mM niacin increased the ce...
Subramaniyam Suresh, Saravanakumar Marimuthu*, Prashanth D’Souza
...t (%), blood beta-hydroxybutyrate (BHB) (mmol/L), and serum cholesterol & triglycerides (mg/dL), and liver marker enzymes (IU/L) viz. aspartate aminotransferase (AST), alanine transaminase (ALT), and gamma-glutamyl transferase (GGT). Results revealed that 4% FCM was numerically improved on week 1 (0.11), week 2 (0.46), week 3 (0.56), and week 4 (0.54) as compared to baseline in PTF supplemented group. Milk fat (%) was also significantly (p < 0.001) impr...
Weijun Chen1*, Shiyang Gao1, Ping Sun1, Xiaohui Sun2, Yongbin Wei1, Jingyang Chen1 and Jialong Chen1
...te the effects of sodium butyrate (NaBT) supplementation in high-fat diets on the growth performance and liver health of common carp (Cyprinus carpio), we formulated three isonitrogenous diets: the control diet (5.8% crude lipid, Control diet), the high-fat diet (10.8% crude lipid, HF diet), and the NaBT diet (10.8 % crude lipid and 0.1% NaBT, NaBT diet). Each diet was assigned to triplicate tanks (100 L) with 24 fish (14.52±0.08 g) in each tank. Experi...
Tahir Rasool Qamar1, Sanaullah Iqbal1*, Muhammad Nasir1 and Habib-ur- Rehman2
...er levels of acetate and butyrate compared to group G2. Group G4 also hindered body weight loss due to carcinogenesis effect. It can be concluded that chicory root powder has protective impact against CRC biomarkers particularly if it is taken as preventive measure.
* Corresponding author: sanaullah.iqbal@uvas.edu.pk
... 
