Huma Naz1,*, Sajid Abdullah2, Sidra Naz3, Sidra Abbas2, Wardah Hassan2, Shakeela Perveen2, Moazama Batool1, Laiba Shafique2
...al concentration. During acute toxicity test, behavioral changes and catalase activity in liver, kidney, gills, brain and muscle of the fish were also studied. The mean 96 h LC50 and lethal value for C. mrigala was determined as 47.56±0.04 and 93.89±0.07 mgL-1, respectively. The selected concentration of Fe+Ni+Pb+Zn concentrations showed strong and direct relationship with, fin movement followed by mucous secretion, h...
Fariha Latif* and Muhammad Javed
...hal concentration. These acute toxicity tests were performed at constant temperature (30oC), pH (8) and total hardness (250 mgL-1). All the three fish species varied significantly in their sensitivity towards metals mixture with the C. catla beingsignificantly highly sensitive followed by L. rohita and C. mrigala. After the acute toxicity tests, fish were exposed to 2/3rd...
Huma Naz1*, Sajid Abdullah2, Khalid Abbas2, Muhammad Rizwan Tariq3, Laiba Shafique4, Ghazala Nazeer5
...tla.
...
Rafia Sadaf1, Ishrat Younus2*, Sidra Maqbool2, Talha Bin Fayyaz3, Sarah Jameel Khan1, Sidra Siddique1 and Rida Fatima1
... is designed to evaluate acute toxicity and anti-anxiety activity of ethanol extract of Pulsatilla nigricans leaves. The acute oral toxicity shows that, plant extract up to 5000 mg/kg produces no signs and symptoms related to toxicity and also no mortality was observed. Antianxiety activity of Pulsatilla nigricans was examined by using elevated plus-maze paradigm and hole-board paradigm in rats at two different doses i.e. 250 and 500 mg/kg, and s...
Grigory Antonovich Nozdrin1*, Regina Gabdrahmanovna Utkina2, Anastasia Aleksandrovna Lelyak2 and Yana Viktorovna Novik1
...y aim to investigate the acute toxicity of the new microbial preparation from a predatory fungus Arthrobotrys oligospora in birds. The experiments were performed on two-days-old goslings and ducklings which were divided into four experimental groups and a reference group. The fowls in experimental groups were supplemented with preparation once with dosages (2,000 µl/kg, 3,000 µl/kg, 4,000 µl/kg, and 5,000 ml/kg) while the fowl in the referenc...
Ibadullah Jan1*, Iqbal Munir2, Inamullah Khan3, Syed Muhammad Suhail4 and Aqib Iqbal2
...gesic along with in vivo acute toxicity in the animal model. Different techniques such as xylene induced ear edema model, Carrageenan induced paw edema model, Hot plate pain model, Ethanoic acid-induced pain model, Yeast instigated pyrexia model acute toxicity model was used to investigate Dosiflavone. Dosiflavone showed significant (p<0.05) reduction of the ear edema at a high dose. However, at 20 mg/kg for 60 minutes, t...
Tooba Ather1, Muhammad Rafiq Shahid2*, Muhammad Ahsin Ayub3, Javed Iqbal2, Muhammad Asim Bhutta2, Muhammad Akram2, Naveeda Anjum4, Muhammad Rizwan6, Hafeezur Rehman5 and Umar Farooq5
Sehrish Akram1, Abida Butt1* and Shakil Ahmad Khan2
...ae compared to lead. The acute toxicity of imidacloprid formulation (IMF), imidacloprid technical grade (IMT) and Pb showed positive correlation with the concentration and negative with the age of larvae. From second to fifth instars, LC50 values of IMF ranges from 0.72 to 2.96, IMT from 0.86 to 2.75 and Pb from 1.93 to 6.88 mg/L. The toxicity of binary mixture of IMF + Pb showed synergism against all instars of silkworm. While, binary mixture of IMT + Pb disp...
Aamir Mushtaq1*, Fatima Habib2, Umar Farooq Gohar3, Abdul Malik4 and Mobasher Ahmad2
...e months. The results of acute toxicity study represented the LD50, value as 4.1 g/Kg/po in albino mice and it was observed that the acute toxic doses produced behavioral changes like hyper-salivation, hyper-secretions, irritation, cyanosis and sedation in mice. Results of chronic toxicity indicated that plant extract did not affect the level of erythrocytes, leukocytes, thrombocytes, hemoglobin, hematocrit, creatinine and liver enzymes (SGOT, SGPT and TB) in ...
