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Effect of AlCl3 Mediated Toxicity on the Hemato-biochemical Profile of Adult Male Albino Mice

Effect of AlCl3 Mediated Toxicity on the Hemato-biochemical Profile of Adult Male Albino Mice

Muhammad Nazar Aftab1, Ahmed Ali1, Muhammad Asad1, Sadia Fatima2 and Furhan Iqbal2,*

1Department of Life Sciences, Zoology Division, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan
2Institute of Pure and Applied Biology, Zoology Division, Bahauddin Zakariya University, Multan 60800, Pakistan

Muhammad Nazar Aftab and Ahmed Ali contributed equally to the manuscript.

ABSTRACT
The aim of this study was to report the effects of AlCl3 mediated toxicity on the hematobiochemical profile of male albino mice. Eight week old male albino mice were used as experimental animals and were divided into two groups. First group was treated with 80mg/Kg body weight of AlCl3 for 16 days while control group was treated with saline solution for the same period of time. Complete blood count were determined in both experimental treatments at the end of dose supplementation. Our results revealed that oral supplementation of 80mg/Kg body weight of AlCl3 for 16 days did not affect (P > 0.05) any of the studied parameters of complete blood count. On the other hand, serological parameters like triglycerides (P = 0.0075 ), total proteins (P = 0.042) and creatinine (P = 0.0038)were significantly higher in treated male mice when compared with their untreated control group indicating the hazardous effects of AlCl3 on blood chemistry of adult male albino mice.

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Pakistan Journal of Zoology

June

Vol. 50, Iss. 3, Pages 799-1198

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