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The Effects of Wumei Pill on TLRs/NF-kB Signaling Pathway in Rats with Diarrhea-Predominant Irritable Bowel Syndrome

The Effects of Wumei Pill on TLRs/NF-kB Signaling Pathway in Rats with Diarrhea-Predominant Irritable Bowel Syndrome

Xiaojie Ding, Xiling Sun, Zuien Wang, Qiusheng Zheng, Xiaofei Yu, Wenjin Hao, Kejun Wang, Wenjuan Xu and Zhengping Dong*

Department of Integrated Traditional Chinese and Western Medicine, Binzhou Medical University, Yantai, 264003, China

*      Corresponding author: dingxiaojie0604@sina.cn

 

 

Fig. 1.

Effect of Wumei Pill on TLR4 expression in chronic mucosal tissue of normal group (A), model group (B), probiotics group (C) and Wumei Pill group (D) rats with dirrhea-predominant irritable bowel syndrome. Magnification: all 100X.

Fig. 2.

Effect of Wumei Pill on TLR9 expression in chronic mucosal tissue of normal group (A), model group (B), probiotics group (C) and Wumei Pill group (D) rats with dirrhea-predominant irritable bowel syndrome. Magnification: all 100X.

Fig. 3.

Effect of Wumei Pill on NF-kB expression in chronic mucosal tissue of normal group (A), model group (B), probiotics group (C) and Wumei Pill group (D) rats with dirrhea-predominant irritable bowel syndrome. Magnification: all 100X.

Fig. 5.

Pathological changes in colonic tissue of normal group (A), model group (B), probiotics group (C) and Wumei Pill group (D) rats with dirrhea-predominant irritable bowel syndrome.

Fig. 4.

Wester Blot showing expression of TLR4, TLR9 and NF-kB in colonic tissue of normal (1), Model (2), Probiotics (3) and Wumei Pill (4) groups of rats with dirrhea-predominant irritable bowel syndrome.

Pakistan Journal of Zoology

December

Vol. 50, Iss. 6, Pages 1999-2398

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