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Studies on the Physical Parameters for Cephalosporin Biosynthesis from Acremonium chrysogenum by Submerged Fermentation

Studies on the Physical Parameters for Cephalosporin Biosynthesis from Acremonium chrysogenum by Submerged Fermentation

Umar Farooq Gohar1, Hamid Mukhtar1,*, Ali Nawaz1, Ikram-ul-Haq1 and Asad Mehmmood2

1Institute of Industrial Biotechnology, GC University, Lahore-54000, Pakistan
2 School of Chemistry, University of New South Wales, Australia

*      Corresponding author: hamidwaseer@yahoo.com

 

Fig. 1.

Optimization of the incubation temperature for the production of cephalosporin by Acremonium chrysogenum in shakes flasks. All the values are means of three parallel replicates. Y-error bars indicate the standard error from mean. Fermentation conditions: incubation period= 144 h.

Fig. 2.

Optimization of incubation period for the production of cephalosporin by Acremonium chrysogenum in shake flasks. All the values are means of three parallel replicates. Y- error bars indicate the standard error from mean. Fermentation conditions: incubation temperature = 30°C, initial pH = 6.6.

Fig. 3.

Effect of the initial pH of culture medium on the production of Cephalosporin by Acremonium chrysogenum in shake flasks. All the values are means of three parallel replicates. Y-error bars indicate the standard error from mean. Fermentation conditions: incubation period=144 h; incubation temperature = 30°C.

Fig. 4.

Effect of inoculum of various sizes and ages on the production of cephalosporin by Acremonium chrysogenum in shake flasks. All the values are means of three parallel replicates. Y- error bars indicate the standard error from mean. Fermentation conditions: Incubation period = 144 h; incubation temperature = 30 °C; pH = 6.5. C, amount of cephalosporin; DMM, dry mycelial mass.

Pakistan Journal of Zoology

December

Vol. 51, Iss. 6, Pages 1999-2399

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