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Redressal of Antibiotic Resistance using Plant Extracts

Adeen Kiran1, Umar Farooq Gohar1*, Ayesha Farooq1, Malik Muhammad Asif2 and Hamid Mukhtar1

1Institute of Industrial Biotechnology, Government College University, Lahore 54000, Pakistan; 2College of Medicine, University of Hail, Hail, Kingdom of Saudi Arabia.
 
*Correspondence | Umar Farooq Gohar, Institute of Industrial Biotechnology, Government College University, Lahore 54000, Pakistan; Email: dr.mufgohar@gcu.edu.pk

ABSTRACT

With the passage of time antibiotic resistance is prevailing in microbes and current drugs are not effective enough to cure infectious diseases caused by these resistant pathogens. In this battle, there is a continuous need to develop new drugs or compounds that can cure these infections or to reverse the antibiotic resistance in these pathogens. In recent years different experimental approaches highlighted the importance of phytochemicals present in plants and its ability to kill these pathogens and microbial inability to develop resistance against these pathogens. Therefore, the trend has been shifting from using synthetic or semi-synthetic antibiotics to the use of medicinal plants which are the part and parcel of traditional medicines. Thus, this review article explains the different mechanisms adopted by microbial life to develop resistance against antibiotics. This article also explains how the resistance can be reversed as well as the bio-medicinal importance of plants and their effectiveness against many pathogens.

 

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Pakistan Journal of Zoology

June

Vol. 53, Iss. 3, Pages 801-1200

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