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Pomegranate Juice Ameliorates Fetotoxic Effects of Atenolol in Developing Mice (Mus musculus)

Pomegranate Juice Ameliorates Fetotoxic Effects of Atenolol in Developing Mice (Mus musculus)

Sara Zafar* and Asmatullah

Department of Zoology, University of the Punjab, Quaid-i-Azam Campus, Lahore 54590, Pakistan

*      Corresponding author: sarazafar1133@gmail.com

Fig. 1.

Morphological results of Control, Vehicle control (VC), High (A, B, C) and Low dose groups (D) and from pomegranate treated dose groups High+PJ (F), Low+PJ (G) and Antidote (only pomegranate juice) group (E); R: Resorbed fetus in uterus, Hm: Hemorrhage, Da: Distorted axis, He: Hyperextension, Hy: Hygroma.

Fig. 2.

Histological sections through the head and facial region of mice embryos from control (A), low (B), high (C) dose groups and from pomegranate treated dose group High+PJ (D) and Antidote (only pomegranate juice) group (E); Sc, spinal cord; Dc, dorsal cerebellum; Tv, third ventricle; Fv,caudal part of fourth ventricle; Ae, anterior chamber of eye; IrS, intra-retinal space; Ssc, semicircular canal; Tc, tentorium cerebelli; IAc, inferior part of anterior commissure; P, Pons; Ns, nasal septum; Nc, nasal cavity; L, lens; Ax, cartilage primordium of rostral part of axis; At, cartilage primordium of anterior arch of atlas; DVs, transverse dural venous sinus; Ac, anterior commissure; Ba, basilar artery; Nr, neural layer of retina; Hc, hyaloid cavity; Pre, pupil of right eye; CPt, cartilage primordium of turbinate bone; Sg, serous gland; Fv*, follicles of vibrassae; P, pons; Rc, right cerebellum; RTv, infendibular recess of third ventricle; SSC, superior semi circular canal; Dc, dorsal cerebellum.

Circumference

Pakistan Journal of Zoology

August

Vol. 52, Iss. 4, Pages 1225-1630

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