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Optimum Conditions for Enhanced Production of Podophyllotoxin from Penicillium sp. Isolated from Khanspur, Pakistan

Optimum Conditions for Enhanced Production of Podophyllotoxin from Penicillium sp. Isolated from Khanspur, Pakistan

Umar Farooq Gohar, Attia Majeed, Bushra Muneer* and Hamid Mukhtar

Institute of Industrial Biotechnology, Government College University, Lahore, Pakistan 54000.

 
* Corresponding author: bushramuneer11@yahoo.co.uk, dr.bushramuneer@gcu.edu.pk

Fig. 1.

Phylogenetic tree of endophytic fungi Penicillium sp. P 18 isolated from Podophyllum hexandrum based on ITS region with top ten most similar sequences.

Fig. 2.

Physical parameters (A): incubation time; (B): Temperature; (C): pH and (D): inoculum size on the production of podophyllotoxin by Penicillium sp. P-18 using surface culture fermentation in YSB medium.

Fig. 3.

Effect of different concentrations of (A) Glucose, (B) Peptone, and (C) Ammonium phosphate on the production of podophyllotoxin by Penicillium sp. P-18 by using surface culture fermentation in YSB medium pH5.5 at 25°C.

Pakistan Journal of Zoology

October

Vol. 54, Iss. 5, Pages 2003-2500

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