M. graminicola Golden and Birchfield (MG) is an important pest of cereal crops. In Pakistan the yield of wheat is extremely low as compared to many other developing countries. Among several factors, responsible for low crop yield, MGis an emerging threat. In vitro hatching percentage of MG was evaluated that was varied significantly at different concentration of chemicals, bio control agents and plant extracts. Among chemicals, cartap was most effective with lowest egg hatching and among biocontrol agents Paecilomyces lilacinus (Thom) Samson (PL) produced highest egg hatching while, Trichoderma harzianum Rifai (TH) caused lowest egg hatching. In plant extracts the highest egg hatching was recorded in clove at S concentration and lowest by neem extracts at S/10 concentration. Cartap and rugby produced 100 % juvenile mortality at S concentration. After 48 h the treatment TH + PL caused highest juvenile mortality of MG and among plant extracts tobacco extract caused the highest juvenile mortality after 48 h. The protective and curative effect of chemicals, biocontrol agents and plant extracts on the development of MG was recorded on the basis of number of eggs on the most susceptible wheat variety cv. ‘Aus -7-58-0850’. In protective effect the highest number of eggs were recorded in rugby treatment. Chemicals were found to be more effective than plant extracts and biocontrol agents. Among biocontrol agents TH produced lowest number of eggs. In curative effect of plant extracts the highest number of eggs were observed in plants treated with in aloe vera extract. Protective and curative treatment with plant extracts, biocontrol agents and chemicals suppressed the disease and enhanced plant height and root weight. All treatments evaluated in this study exhibited suppression of MG. Therefore, these treatments can be used in combination against MG infestation on wheat.