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In-vitro Growth Inhibition and Biofilm Dispersion of Caries causing Streptococcus mutans by the Natural Extracts of Soil Streptomyces

In-vitro Growth Inhibition and Biofilm Dispersion of Caries causing Streptococcus mutans by the Natural Extracts of Soil Streptomyces

Ayesha Munir, Hafiz Muhammad Umer, Anjum Nasim Sabri and Imran Sajid*

Department of Microbiology and Molecular Genetics, University of the Punjab, Lahore 54590

*      Corresponding author: imran.mmg@pu.edu.pk

 

Fig. 1.

Normalized biofilm formation by S. mutans at 48, 72 and168 rhs (bars) and their respective planktonic growth (lines) under influence of natural extracts at different concentration (0, 100, 200, 400, 800 and 1600 µg/mL) from Strptomyces strain HU-9.

Fig. 2.

Normalized biofilm formation by S. mutans at 48, 72 and168 rhs (bars) and their respective planktonic growth (lines) under influence of natural extracts at different concentration (0, 100, 200, 400, 800 and 1600 µg/mL) from Strptomyces strain HU-10.

Fig. 3.

 HPLC-UV chromatogram of strain HU-16. There are major four peaks in chromatogram at different retention times. The fraction of secondary metabolite at retention time 5.47 is abundant in crude extract from this strain.

Pakistan Journal of Zoology

October

Vol. 50, Iss. 5, Pages 1601-1998

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