Identification of Circulating miRNAs as Non-Invasive Biomarkers of Triple Negative Breast Cancer in the Population of Pakistan
Jawaria Shaheen1, Samiah Shahid1, Sabahat Shahzadi2, M. Waheed Akhtar1,3 and Saima Sadaf1,*
Scatter plots are representing high expression fold change in mir-376c, mir-155, mir-17a and mir-10b with significant p-value (p< 0.05).
Box and Whisker plots are showing stage, grade, tumour size, lymph nodes involvement and metastasis association with mir-155, mir-376c, mir-10b and mir-17a, respectively in TNBC patient’s plasma samples.
Receiving Operating Curves (ROC) representing AUC, sensitivity and specificity of mir-376c, mir-155, mir-17a and mir-10b and comparison of miRNA panel for the assessment of biomarkers diagnostic outcome in TNBC vs non-TNBC.