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Effect of Vitamin E Supplementation on Humoral Immunity Following the Administration of Enterotoxaemia Vaccine in Goats

Effect of Vitamin E Supplementation on Humoral Immunity Following the Administration of Enterotoxaemia Vaccine in Goats

Mumtaz Ali Khan1,*, Sher Bahadar Khan2, Shakoor Ahmad2, Irshad Ahmad3, Ikramul Haq4, Kashif Prince1, Asad Ullah5, Muhammad Shoaib2, Shahid Zaman6, Amjad Islam Aqib7, Ghazunfar Rashid1, Mahboob Ali1, Imdad Ullah Khan4,Imad Khan5, Naimat Ullah4 and Muhammad Shahid8

1Department of Clinical Medicine and Surgery, University of Veterinary and Animal Sciences, Lahore
2Department of Animal Health, the University of Agriculture, Peshawar
3Instutute of Basic Medical Sciences, Khyber Medical University, Peshawar
4Gomal College of Veterinary Sciences, Gomal University, D.I. Khan
5College of Veterinary Sciences and Animal Husbandry, Abdul Wali Khan University, Mardan
6Department of Microbiology, Faculty of Biological Sciences, Quaid e Azam University, Islamabad
7Department of Clinical Medicine and Surgery, University of Agriculture, Faisalabad
8Veterinary Research Institute, Peshawar, Khyber Pakhtunkhwa

*     Corresponding author: dr_mumtazkhan@yahoo.com 

 

ABSTRACT

This study was conducted to evaluate and compare the effects of vitamin E supplementation on humoral immunity against Clostridium perfringens type D epsilon toxin in goats to sort out better immunogenic approach. This study was conducted on total of 36 healthy animal of equal number of rabbits and goats. Each species was divided randomly into three equal (n=6) groups. Group A was supplemented vitamin E and group B was without vitamin E supplementation in both species. Animals of both groups were vaccinated with enterotoxaemia vaccine. Group C was kept as negative control in both rabbits and goats. The immune titer against C. perfringens type D was evaluated on 0, 7, 14, 28th and 60th day of vaccination with indirect haemagglutination test (IHA). The results showed significantly higher (P< 0.05) immune titer in vitamin E supplemented animals groups against C. perfringens type D epsilon toxin.
 

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Pakistan Journal of Zoology

December

Vol. 51, Iss. 6, Pages 1999-2399

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