The concept of using different brooding systems was evaluated by using 720 day-old commercial broilers, 240 from each of the 3 strains (Ross 308, Cobb 500, Hubbard classic). All the chicks having uniform body weight were randomly distributed into 36 replicates having 20 birds each according to completely randomized design and were fed the same quantity of feed. The birds were subjected to 4 heating systems during brooding (Floor Heating, Diesel, Gas and Electricity Bulb). Growth performances, blood glucose, cholesterol level and economic appraisal in term of running cost / Kg of live meat were recorded. The results revealed that all strains generally but Ross 308 particularly maintained on floor heating system (FH) exhibited significantly (P<0.05) better FCR, EEF and livability along with higher glucose and lower cholesterol level in blood with better immune response that led to higher profit margin. All these parameters were significantly (P<0.05) lowest on gas brooder in comparison of brooding systems.