Effect of Administration of Mercuric Chloride on the Social Behavior, Neuromuscular Coordination, Motor Activity, Blood Parameters and Liver Structure Alterations in Mice Offspring
Gasem Mohammad Abu-Taweel
Effect of perinatal exposure to Hg on neuromuscular coordination in mice offspring.* and ** showed significant variation at P < 0.05 and P < 0.01 level respectively compared with control group by ANOVA and student’s t-test.
Perinatal Hg exposure effects on locomotor activity behavior of mice offspring.*** shows statistically significant variation at P < 0.001 level than control group by ANOVA and student’s t-test.
Effect of Hg toxicity on red blood cells (A), volume of packed red cells (B), hemoglobin content of mice (C), white blood cells (D), platelets (E) of mice offspring. *, ** and *** implied significant different at p<0.05, p<0.01 and p<0.001 level respectively from the control group by ANOVA.
Effect of Hg on random glucose level (A), gamma glutamyl transferase (B). *, ** and *** significantly different at (p<0.05, p<0.01 and p<0.001) respectively from the control group by ANOVA student’s t-test.
Effect of Hg on liver histology x400. A, Liver plate (control) showed: normal tissue. B, liver (5 ppm) showed: drug induced mild mixed mononuclear inflammatory cells with little esinophiles, congested capillaries and hydropic degenerations.C,liver (10 ppm) showed: drug induced mixed mononuclear inflammatory cells with esinophiles and dilated capillaries and hydropic degenerations.