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Effect of Administration of Mercuric Chloride on the Social Behavior, Neuromuscular Coordination, Motor Activity, Blood Parameters and Liver Structure Alterations in Mice Offspring

Effect of Administration of Mercuric Chloride on the Social Behavior, Neuromuscular Coordination, Motor Activity, Blood Parameters and Liver Structure Alterations in Mice Offspring

Gasem Mohammad Abu-Taweel

Department of Biology, College of Sciences, Jazan University, P.O. Box 2079, Jazan 45142, Saudi Arabia

*      Corresponding author: gmabutaweel@jazanu.edu.sa; abutaweelbiochem@gmail.com

 

Fig. 1.

Effect of perinatal exposure to Hg on neuromuscular coordination in mice offspring.* and ** showed significant variation at P < 0.05 and P < 0.01 level respectively compared with control group by ANOVA and student’s t-test.

Fig. 2.

Perinatal Hg exposure effects on locomotor activity behavior of mice offspring.*** shows statistically significant variation at P < 0.001 level than control group by ANOVA and student’s t-test.

Fig. 3.

Effect of Hg toxicity on red blood cells (A), volume of packed red cells (B), hemoglobin content of mice (C), white blood cells (D), platelets (E) of mice offspring. *, ** and *** implied significant different at p<0.05, p<0.01 and p<0.001 level respectively from the control group by ANOVA.

Fig. 4.

Effect of Hg on random glucose level (A), gamma glutamyl transferase (B). *, ** and *** significantly different at (p<0.05, p<0.01 and p<0.001) respectively from the control group by ANOVA student’s t-test.

Fig. 5.

Effect of Hg on liver histology x400. A, Liver plate (control) showed: normal tissue. B, liver (5 ppm) showed: drug induced mild mixed mononuclear inflammatory cells with little esinophiles, congested capillaries and hydropic degenerations.C,liver (10 ppm) showed: drug induced mixed mononuclear inflammatory cells with esinophiles and dilated capillaries and hydropic degenerations.

Pakistan Journal of Zoology

June

Vol. 52, Iss. 3, Pages 825-1224

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