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Effect of Gross Saponins of Tribulus terrestris on IL-1β-induced Chondrocyte Injury by Regulating miR-99a Expression

Effect of Gross Saponins of Tribulus terrestris on IL-1β-induced Chondrocyte Injury by Regulating miR-99a Expression

Ji Xu, Zhonghua Liu, Zhenhai Cui and Wenhai Zhao*

College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, 130117, China.

 
* Corresponding author: zwh13029146408@163.com

Fig. 1.

Effect of gross saponins of Tribulus terrestris on IL-1β chondrocyte apoptosis. A, Expression of apoptosis-associated proteins; B, Apoptotic flow pattern.

Fig. 2.

Effect of miR-99a overexpression on il-1β-induced chondrocyte apoptosis. A, Expression of apoptosis-associated proteins; B, Apoptotic flow pattern.

Fig. 3.

The effect of gross saponins of Tribulus terrestris (100 mg/L) on IL-1β-induced chondrocyte damage was reversed by inhibition of miR-99a. A, Expression of apoptosis-associated proteins; B, Apoptotic flow pattern.

Pakistan Journal of Zoology

August

Vol. 54, Iss. 4, Pages 1501-2001

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