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Comparative Evaluation of Live Vector, Immune Complex and Intermediate Plus Vaccines of Infectious Bursal Disease in Broiler Chicken

Comparative Evaluation of Live Vector, Immune Complex and Intermediate Plus Vaccines of Infectious Bursal Disease in Broiler Chicken

Rana Waqas Arshad1, Asim Aslam1, Muhammad Saeed Imran1, Kamran Ashraf2 and Raheela Akhtar1,*

1Department of Pathology, University of Veterinary and Animal Sciences, Lahore 54000
2Department of Parasitology, University of Veterinary and Animal Sciences, Lahore 54000

*  Corresponding author: raheela.akhtar@uvas.edu.pk

 

ABSTRACT

The aim of the present study was to compare commercially available vaccines of infectious bursal disease (IBD). Three experimental groups, each having 100 broiler birds were placed in the same environmentally controlled house. Samples of blood and bursa of Fabricius were collected from slaughtered birds after every 7 days till the end of experiment (35 days). The size of bursas and the bursa/body weight ratios were significantly greater in live vector vaccine group than other vaccinal groups. ELISA revealed high antibody titre in live vector vaccine group and a partial protection was observed in birds vaccinated with immune complex or intermediate plus vaccines. Consistently, histopathological lesions of IBD were less evident in live vector vaccine group in comparison to other groups. In addition live vector vaccine improved the feed conversion ratio (FCR) by keeping the bird healthy and by decreasing the immunosuppression. These results indicated that live vector vaccine has overall positive impact in terms of immunity, histopathology of bursa of Fabricius and FCR. These results can be implemented in field for complete protection and better growth performance of broiler industry.
 

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Pakistan Journal of Zoology

August

Vol. 51, Iss. 4, Pages 1203-1598

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