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Antiviral Roles of Artificial microRNAs

Antiviral Roles of Artificial microRNAs

Huaichang Sun

College of Veterinary Medicine, Jiangsu Co-Innovation Center for Prevention and Control of Important Animal infectious Diseases and Zoonoses, Yangzhou University, Yangzhou 225009, China.

E-mail | sunh@yzu.edu.cn

ABSTRACT

Many RNA viruses undergo rapid mutations which compromises the immune protection of conventional vaccines. RNA interference (RNAi) has becoming a feasible strategy against various virus infections. Recently, a significant advance in RNAi technology is the use of artificial microRNAs (amiRNAs) to fight virus infections. However, different strategies are needed to prevent virus variation or mutation escape. This review is intended to present the current situation of antiviral roles of amiRNAs, against variable RNA viruses in particular.

 

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Hosts and Viruses

June

Vol.6, Iss.3, Pages 42-84

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