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A Virus-like Particle Vaccine Against Infectious Bursal Disease Virus: Potential Uses and Applications

A Virus-like Particle Vaccine Against Infectious Bursal Disease Virus: Potential Uses and Applications

Kang-Seuk Choi

OIE Reference laboratory for Newcastle Disease, Avian Disease Division, Animal and Plant Quarantine Agency, 177 Hyeok- sin 8-ro, Gimcheon-si, Gyeongsangbukdo, 39660, Republic of Korea.

E-mail | kchoi0608@korea.kr

ABSTRACT

Infectious bursal disease (IBD) virus-like particles (VLPs) comprising only viral capsid proteins mimic the naive configuration of authentic IBD virus particles. The VLPs show intrinsic immunogenicity and a high safety profile.  Thus, VLPs are considered one of the most promising approaches to vaccine development and are an alternative to inactivated IBD vaccines. In addition, VLP technology has many applications. This paper reviews the potential of VLPs as an alternative to IBD vaccines, along with their specific applications in the field.

 

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Hosts and Viruses

June

Vol.6, Iss.3, Pages 42-84

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