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Evaluation of Hemato-Biochemical Parameters, Histopathological Altration and Antioxidant Trace Elements in Demodicosis Infected Dogs

Evaluation of Hemato-Biochemical Parameters, Histopathological Altration and Antioxidant Trace Elements in Demodicosis Infected Dogs

Noha M El-Motaily1, Ossama M Abdou1, Heba S Farag1, Kawkab A Ahmed2, Mahmoud Saber1*

1Department of Medicine and Infectious Diseases, Faculty of Veterinary Medicine, Cairo University, Egypt; 2Department of Pathology, Faculty of Veterinary Medicine, Cairo University, Egypt.

 
*Correspondence | Mahmoud Saber, Department of Medicine and Infectious Diseases, Faculty of Veterinary Medicine, Cairo University, Egypt; Email: Mahmoud.saber@vet.cu.edu.eg

ABSTRACT

Canine demodicosis is a misery that causes panic to pet owners and caused by excessive proliferation of the normal skin commensal Demodex mites. Hemato-biochemical changes were previously reported in patient dogs with demodicosis due to the effect of stress caused by mites. This study was conducted on 38 dogs, 20 of them were used as control group and 18 were demodicosis infected dogs, for evaluation of hematological, biochemical and histopathological alterations. Beside detection of the antioxidant trace elements (Zn, Cu, Se) levels in dogs suffering from demodicosis. Results showed significant decrease in the value of (PCV) and (TEC). Affected dogs also showed leukocytosis associated with lymphocytosis. Hypothyroidism demonstrated by reduced levels of free T4 and significant decrease in antioxidant trace elements level (Zn, Cu, Se).
 
Keywords | Antioxidant trace elements, Biochemistry, Canine demodicosis, Hematology, Histopathology

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Advances in Animal and Veterinary Sciences

May

Vol. 12, Iss. 5, pp. 802-993

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