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Detection of Cytomegalovirus in Pregnant Women of Lakki Marwat and Bannu, Khyber Pakhtunkhwa, Pakistan

Detection of Cytomegalovirus in Pregnant Women of Lakki Marwat and Bannu, Khyber Pakhtunkhwa, Pakistan

Faryal Saad1,3, Zia Ur Rahman2, Aamir Khan3, Rabia Noushin4, Irfan Ullah5, Farman Ullah Dawar3,Shahid Naiz Khan3, Rafiqe Hussain6, Kenza Javed2Abid ur Rehman7, Amna Fayaz3, Zohra Saifullah3 and Kalim Ullah3*

1Department of Zoology, Abdulwali Khan University, Mardan, Pakistan
2Department of Biotechnology and Genetic Engineering, Kohat University of Science and Technology, 26000, Khyber Pakhtunkhwa, Pakistan
3Department of Zoology, Kohat University of Science and Technology, 26000, Khyber Pakhtunkhwa, Pakistan
4Department of Botany, Kohat University of Science and Technology, 26000, Khyber Pakhtunkhwa, Pakistan
5Department of Biological Sciences, Karakoram International University, Ghizar Campus, 15200, Pakistan
6Department of Zoology, University of Lakki Marwat, Khyber Pakhtunkhwa, Pakistan
7Department of Zoology, Government Post Graduate College Bannu

*      Corresponding author: dr.kalim@kust.edu.pk

ABSTRACT

 Cytomegalovirus (CMV) infection is the most common cause of both congenital and intrauterine infection in developing fetus and pregnant women respectively. Proper in-time diagnosis of CMV is the most effective way to control this disease. Lack of health care facilities and proper screening of pregnant women for various congenital infections in the Sothern districts of Khyber Pakhtunkhwa, making the situation more worst. Therefore, this preliminary study was set to assess the seroprevalence and molecular detection of CMV infection among pregnant women of districts Lakki Marwat and Bannu of Khyber Pakhtunkhwa. A total of 188 blood samples were randomly collected from pregnant women of both districts and were examined through Enzyme-Linked Immunosorrbent Assay (ELISA) and Polymerase Chain Reaction (PCR) for CMV. Out of total 88 samples, 73.40% were positive for CMV through ELISA and 57.44% were positive for CMV through PCR respectively.

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Pakistan Journal of Zoology

April

Pakistan J. Zool., Vol. 56, Iss. 2, pp. 503-1000

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